925932-08-7

925932-08-7 structure

Name: secaubryenol
Chemical Name: 3-[(1R,3aS,3bS,6R,6aR,7aS,9aR)-6-(3-Hydroxy-1-propen-2-yl)-3a,9a- dimethyl-1-[(2R)-6-methyl-5-hepten-2-yl]decahydro-1H-cyclopenta[a ]cyclopropa[e]naphthalen-6a(7H)-yl]propanoic acid
CAS Number: 925932-08-7
Molecular Formula: C₃₀H₄₈O₃
Molecular Weight: 456.700
Catalog: Natural product Moss
Create Date: 2016-04-10 12:08:23
Modify Date: 2025-08-21 09:01:48
Secaubryenol is a class of 3,4-secocycloartane triterpenes isolated from Coussarea macrophylla. Secaubryenol does not display any cytotoxic effect at a dose of 10 µg/mL[1][2][3].

Name	3-[(1R,3aS,3bS,6R,6aR,7aS,9aR)-6-(3-Hydroxy-1-propen-2-yl)-3a,9a- dimethyl-1-[(2R)-6-methyl-5-hepten-2-yl]decahydro-1H-cyclopenta[a ]cyclopropa[e]naphthalen-6a(7H)-yl]propanoic acid
Synonyms	3-[(1R,3aS,3bS,6R,6aR,7aS,9aR)-6-(3-Hydroxy-1-propen-2-yl)-3a,9a-dimethyl-1-[(2R)-6-methyl-5-hepten-2-yl]decahydro-1H-cyclopenta[a]cyclopropa[e]naphthalen-6a(7H)-yl]propanoic acid 1H-Cyclopenta[a]cyclopropa[e]naphthalene-6a(7H)-propanoic acid, 1-[(1R)-1,5-dimethyl-4-hexen-1-yl]decahydro-6-[1-(hydroxymethyl)ethenyl]-3a,9a-dimethyl-, (1R,3aS,3bS,6R,6aR,7aS,9aR)-

Description	Secaubryenol is a class of 3,4-secocycloartane triterpenes isolated from Coussarea macrophylla. Secaubryenol does not display any cytotoxic effect at a dose of 10 µg/mL[1][2][3].
Related Catalog	Research Areas >> Others
In Vitro	Secaubryenol exhibits IC50 value over 100 µM against tumor cell lines (MCF-7 (breast cancer cells, ER (estrogen receptor) positive), MDA (breast cancer cells, ER negative), PC-3 (prostate cancer cells), and HeLa (cervical cancer cells))[1].
References	[1]. Grougnet R, et al. Cytotoxic 3,4-seco-cycloartane triterpenes from the exudate of Gardenia tubifera. J Nat Prod. 2006 Dec;69(12):1711-4. [2]. Gilardoni G, et al. New 3,4-Secocycloartane and 3,4-Secodammarane Triterpenes from the Ecuadorian Plant Coussarea macrophylla. Chem Biodivers. 2015 Jun;12(6):946-54. [3]. ThanesuanNuanyai, et al. Cycloartane triterpenes from the exudate of Gardenia thailandica. Phytochemistry Letters. Volume 4, Issue 1, 15 March 2011, Pages 26-29.

Hazard Codes	Xi