1207181-59-6

1207181-59-6 structure

Name: Scutebata C
Chemical Name: (1R,2S,3R,4S,4aS,8aR)-4-[(1S)-1-Acetoxy-2-(4-hydroxy-5-oxo-2,5-di hydro-3-furanyl)ethyl]-2,3-dihydroxy-3,4,8,8a-tetramethyl-1,2,3,4 ,4a,5,6,8a-octahydro-1-naphthalenyl nicotinate
CAS Number: 1207181-59-6
Molecular Formula: C₂₈H₃₅NO₉
Molecular Weight: 529.58
Catalog: Natural product Moss
Create Date: 2016-01-30 21:39:59
Modify Date: 2025-08-26 19:26:10
Scutebata C is a neoclerodane diterpenoid isolated from Scutellaria barbata with weak cytotoxic activity[1].

Name	(1R,2S,3R,4S,4aS,8aR)-4-[(1S)-1-Acetoxy-2-(4-hydroxy-5-oxo-2,5-di hydro-3-furanyl)ethyl]-2,3-dihydroxy-3,4,8,8a-tetramethyl-1,2,3,4 ,4a,5,6,8a-octahydro-1-naphthalenyl nicotinate
Synonyms	3-Pyridinecarboxylic acid, (1R,2S,3R,4S,4aS,8aR)-4-[(1S)-1-(acetyloxy)-2-(2,5-dihydro-4-hydroxy-5-oxo-3-furanyl)ethyl]-1,2,3,4,4a,5,6,8a-octahydro-2,3-dihydroxy-3,4,8,8a-tetramethyl-1-naphthalenyl ester (1R,2S,3R,4S,4aS,8aR)-4-[(1S)-1-Acetoxy-2-(4-hydroxy-5-oxo-2,5-dihydro-3-furanyl)ethyl]-2,3-dihydroxy-3,4,8,8a-tetramethyl-1,2,3,4,4a,5,6,8a-octahydro-1-naphthalenyl nicotinate

Description	Scutebata C is a neoclerodane diterpenoid isolated from Scutellaria barbata with weak cytotoxic activity[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Scutebata C 具有弱细胞毒性，对 LoVo、MCF-7、SMMC-7721 和 HCT-116 细胞的 IC50 值分别为47.15 μM，33.18 μM，38.79 μM，大于100 μM[1]。
References	[1]. Wang M, et al. Cytotoxic Neo-Clerodane Diterpenoids from Scutellaria barbata D.Don. Chem Biodivers. 2019 Feb;16(2):e1800499.

Hazard Codes	Xi