Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Methyl-4-(1-piperazinyl)-10H-thienol[2,3-b][1,5]benzodiazepine
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Purity: 98.0%
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161696-76-0

161696-76-0 structure

161696-76-0 structure

Name: 2-Methyl-4-(1-piperazinyl)-10H-thienol[2,3-b][1,5]benzodiazepine
Chemical Name: N-Demethyl Olanzapine
CAS Number: 161696-76-0
Molecular Formula: C₁₆H₁₈N₄S
Molecular Weight: 298.41
Catalog: analytical chemistry Standard standard material
Create Date: 2018-12-27 01:00:55
Modify Date: 2024-01-02 16:57:43
N-Desmethylolanzapine is an antipsychotic drug.The formation of N-Desmethylolanzapine correlates with the level and activityof human liver flavin-containing monooxygenase (FMO3). N-Desmethylolanzapinecan be used in the study of antipsychotic drugs [1].

Name	N-Demethyl Olanzapine
Synonyms	Desmethylolanzapine dihydrochloride 2-methyl-4-piperazin-1-yl-5H-thieno[3,2-c][1,5]benzodiazepine

Description	N-Desmethylolanzapine is an antipsychotic drug.The formation of N-Desmethylolanzapine correlates with the level and activityof human liver flavin-containing monooxygenase (FMO3). N-Desmethylolanzapinecan be used in the study of antipsychotic drugs [1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Ring BJ, et al. Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine. J Pharmacol Exp Ther. 1996 Feb;276(2):658-66.

Density	1.38g/cm3
Boiling Point	489.2ºC at 760 mmHg
Melting Point	144.5ºC
Molecular Formula	C₁₆H₁₈N₄S
Molecular Weight	298.41
Flash Point	249.7ºC
Exact Mass	298.12500
PSA	67.90000
LogP	2.93730
Vapour Pressure	1.02E-09mmHg at 25°C
Index of Refraction	1.742
Storage condition	-20°C Freezer

Symbol	GHS02, GHS07
Signal Word	Danger
Hazard Statements	H225-H302-H319
Precautionary Statements	P210-P305 + P351 + P338
Hazard Codes	F,Xn
Risk Phrases	11-20/21/22-36
Safety Phrases	16-26-36/37
RIDADR	UN 1648 3 / PGII
HS Code	2934999090

930836-40-1 structure

930836-40-1

~95%

161696-76-0 structure

161696-76-0

Literature: Gao, Mingzhang; Shi, Zenas; Wang, Min; Zheng, Qi-Huang Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 7 p. 1953 - 1956

1428146-26-2 structure

1428146-26-2

~75%

161696-76-0 structure

161696-76-0

Literature: Gao, Mingzhang; Shi, Zenas; Wang, Min; Zheng, Qi-Huang Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 7 p. 1953 - 1956

110-85-0 structure

110-85-0

612503-08-9 structure

612503-08-9

~%

161696-76-0 structure

161696-76-0

Literature: WO2007/77134 A1, ; Page/Page column 7 ;

138564-59-7 structure

138564-59-7

~%

161696-76-0 structure

161696-76-0

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 1 p. 25 - 30

138564-58-6 structure

138564-58-6

~%

161696-76-0 structure

161696-76-0

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 1 p. 25 - 30

Precursor 5
1428146-26-2 110-85-0 612503-08-9 138564-59-7
138564-58-6
DownStream 1
132539-06-1

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%