Zhejiang Hangyu API Co., Ltd
China
Product Name: Z-Phe-Arg-AMC
Price: $Inquiry/1kg
Purity: 99.0%
Stocking Period: 1 Day
Contact: Vinnie

65147-22-0

65147-22-0 structure

65147-22-0 structure

Name: Z-Phe-Arg-AMC · HCl
Chemical Name: Z-Phe-Arg 7-amido-4-methylcoumarin hydrochloride
CAS Number: 65147-22-0
Molecular Formula: C₃₃H₃₆N₆O₆
Molecular Weight: 612.68
Catalog: Research Areas Others
Create Date: 2018-11-22 06:53:27
Modify Date: 2024-01-07 16:00:46
N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes[1][2].

Name	Z-Phe-Arg 7-amido-4-methylcoumarin hydrochloride
Synonyms	benzyl N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-2-[(4-methyl-2-oxochromen-7-yl)amino]pentanoyl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate MFCD00077030

Description	N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Xu P, et al. Ascorbic acid modulation of iron homeostasis and lysosomal function in trabecular meshwork cells. J Ocul Pharmacol Ther. 2014 Mar-Apr;30(2-3):246-53. [2]. Porter K,et al. Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis. Autophagy. 2013 Apr;9(4):581-94.

Density	1.32 g/cm3
Molecular Formula	C₃₃H₃₆N₆O₆
Molecular Weight	612.68
Exact Mass	648.24600
PSA	188.64000
LogP	6.17340
Index of Refraction	1.639
Storage condition	-20°C

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3