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35597-43-4 71048-99-2

35597-43-4

35597-43-4 structure
35597-43-4 structure
  • Name: bilanafos
  • Chemical Name: bilanafos
  • CAS Number: 35597-43-4
  • Molecular Formula: C11H22N3O6P
  • Molecular Weight: 323.28300
  • Catalog: API Antibiotics Other antibiotics
  • Create Date: 2018-08-14 13:43:10
  • Modify Date: 2024-01-05 18:25:04
  • Bilanafos is a natural organic phosphine tripeptide antibiotic metabolized by Streptomyces hydroscopius or Streptomyces viridochromeogenes. Bialaphos has antimicrobial activity aganist Gram-negative and positive bacteria as well as some fungal plant diseases[1].
Name bilanafos
Synonyms (2S)-2-amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl-L-alanine
bialaphos
(2S)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyryl-L-alanyl-L-alanine
Bilanafos [ISO]
L-Alanine,4-(hydroxymethylphosphinyl)-L-2-aminobutanoyl-L-alanyl
acide diprogulique
Bialaphos
Antibiotic SF 1293
Phosphinothricylalanylalanine
Bilanafos
(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoyl]amino]propanoyl]amino]propanoic acid
Description Bilanafos is a natural organic phosphine tripeptide antibiotic metabolized by Streptomyces hydroscopius or Streptomyces viridochromeogenes. Bialaphos has antimicrobial activity aganist Gram-negative and positive bacteria as well as some fungal plant diseases[1].
Related Catalog
References

[1]. Takeshi Murakami, et al.The bialaphos biosynthetic genes ofStreptomyces hygroscopicus: Molecular cloning and characterization of the gene cluster. Molecular and General Genetics MGG volume 205, pages42–53 (1986)

Density 1.33g/cm3
Boiling Point 793.2ºC at 760 mmHg
Melting Point 159-161ºC
Molecular Formula C11H22N3O6P
Molecular Weight 323.28300
Flash Point 433.5ºC
Exact Mass 323.12500
PSA 182.29000
Index of Refraction 1.517
Storage condition Store dry at -4

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AY6826000
CHEMICAL NAME :
L-Alanine, gamma-(hydroxymethylphosphinyl)-L-alpha-aminobutyryl- L-alanyl-
CAS REGISTRY NUMBER :
35597-43-4
LAST UPDATED :
199604
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C11-H22-N3-O6-P
MOLECULAR WEIGHT :
323.33
WISWESSER LINE NOTATION :
QVY1&MVY1&MVYZ2PHO&1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),223,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),223,1980
Hazard Codes Xn
Risk Phrases R20/21/22
Safety Phrases 26-36

Chemsrc provides CAS#:35597-43-4 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 35597-43-4 | Chemsrc address: https://www.chemsrc.com/en/baike/951397.html

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