5442-12-6

5442-12-6 structure

Name: Norcantharidin
Chemical Name: Norcantharidin
CAS Number: 5442-12-6
Molecular Formula: C₈H₈O₄
Molecular Weight: 168.147
Catalog: API Antineoplastic agents Natural source antineoplastic agents
Create Date: 2018-08-02 16:29:16
Modify Date: 2024-01-02 18:01:03

Name	Norcantharidin
Synonyms	hexahydro-4,7-epoxyisobenzofuran-1,3-dione cis-exo-hexahydro-4,7-epoxyisobenzofuran-1,3-dione 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic Anhydride Demehylcantharidin Wln: T C555 A ao dvovtj Hexahydro-3,6-epoxyphthalic anhydride demethylcantharidin Nocantharidin 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro- 4,10-Dioxatricyclo[5.2.1.0]decane-3,5-dione 3,6-Endooxyphthalic anhydride,hexahydro

Density	1.5±0.1 g/cm3
Boiling Point	362.5±35.0 °C at 760 mmHg
Molecular Formula	C₈H₈O₄
Molecular Weight	168.147
Flash Point	167.0±26.0 °C
Exact Mass	168.042252
PSA	52.60000
LogP	-0.85
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.550

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RN8300000

CHEMICAL NAME :: 7-Oxabicyclo(2.2.1)heptane-2,3-dicarboxylic anhydride

CAS REGISTRY NUMBER :: 5442-12-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H8-O4

MOLECULAR WEIGHT :: 168.16

WISWESSER LINE NOTATION :: T C555 A AO DVOVTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#05066

Hazard Codes	Xi
WGK Germany	3
RTECS	RN8400000
HS Code	2942000000

5426-09-5

~98%

5442-12-6

Literature: THE CHINESE UNIVERSITY OF HONG KONG Patent: EP1749831 A1, 2007 ; Location in patent: Page/Page column 5; 6 ;

28871-63-8

~99%

5442-12-6

Literature: Salvati, Mark E.; Mitt, Toomas; Patel, Ramesh N.; Hanson, Ronald L.; Brzozowski, David; Goswami, Animesh; Chu, Linda Nga Hoong; Li, Wen-sen; Simpson, James H.; Totleben, Michael J.; He, Weixuan Patent: US2005/119228 A1, 2005 ; US 20050119228 A1

Precursor 2
5426-09-5 28871-63-8
DownStream 3
129-67-9 16131-62-7 16131-73-0

HS Code	2942000000