76497-13-7

76497-13-7 structure

Name: Sultamicillin
Chemical Name: sultamicillin
CAS Number: 76497-13-7
Molecular Formula: C₂₅H₃₀N₄O₉S₂
Molecular Weight: 594.657
Catalog: API Antibiotics Beta-lactamase inhibitor
Create Date: 2018-09-04 09:40:37
Modify Date: 2024-01-03 12:33:54
Sultamicillin is an orally active double prodrug of Ampicillin/Sulbactan. Sulbactam is a semisynthetic beta-lactamase inhibitor which, in combination with Ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would otherwise be resistant[1].

Name	sultamicillin
Synonyms	6'-(2-Amino-2-phenylacetamido)penicillanoyloxymethylpenicillanate 1,1-dioxide Sultancillin alkali 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, [[[(2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-yl]carbonyl]oxy]methyl ester, 4,4-dioxide, (2S,5R)- Unacid PD SultaMcillin Base VD 1827 1,1-Dioxopenicillanoyloxymethyl 6-(D-a-amino-a-phenylacetamido)penicillanate ({[(2S,5R,6R)-6-{[(2R)-2-Amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-yl]carbonyl}oxy)methyl (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide Sultamicillin Bethadl Orale Sultamicillin Base Baeimex

Description	Sultamicillin is an orally active double prodrug of Ampicillin/Sulbactan. Sulbactam is a semisynthetic beta-lactamase inhibitor which, in combination with Ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would otherwise be resistant[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Friedel HA, et al. Sultamicillin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1989 Apr;37(4):491-522.

Density	1.6±0.1 g/cm3
Boiling Point	907.7±65.0 °C at 760 mmHg
Melting Point	190°
Molecular Formula	C₂₅H₃₀N₄O₉S₂
Molecular Weight	594.657
Flash Point	502.8±34.3 °C
Exact Mass	594.145447
PSA	216.16000
LogP	-0.29
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.668
Storage condition	2-8°C
Water Solubility	Practically insoluble in water, very slightly soluble in methanol, practically insoluble in ethanol (96 per cent).

HS Code	2934999090

Precursor 2
76247-39-7 69-52-3
DownStream 0

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%