172670-99-4

172670-99-4 structure

Name: N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone
Chemical Name: 3-Hydroxy-N-(tetrahydro-2-oxo-3-furanyl)tetradecanamide
CAS Number: 172670-99-4
Molecular Formula: C₁₈H₃₃NO₄
Molecular Weight: 327.45900
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2016-07-12 04:35:20
Modify Date: 2024-01-08 09:22:03
N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (N-(3-oxodecanoyl)-homoserine lactone) is a member of N-Acyl homoserine lactone (AHL) from V. alginolyticus strains. N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone is used for biofilm formation and has antibacterial activity[1].

Name	3-Hydroxy-N-(tetrahydro-2-oxo-3-furanyl)tetradecanamide
Synonyms	N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone 3-hydroxy-N-(2-oxooxolan-3-yl)tetradecanamide

Description	N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (N-(3-oxodecanoyl)-homoserine lactone) is a member of N-Acyl homoserine lactone (AHL) from V. alginolyticus strains. N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone is used for biofilm formation and has antibacterial activity[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Moderate levels of exogenous N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (N-(3-oxodecanoyl)-homoserine lactone; 10 and 20 μM) can induce or enhance biofilm formation and alter its structure, while high levels (40 and 100 μM) does not significantly improve and even inhibits biofilm formation in V. alginolyticus[1]. N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (2, 5, 10, 20 μM; 36 hours) increases the biofilms of strain N°24 significantly[1]. Moderate addition of N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (10 or 20 μM) also increases biofilm formation of non-AHL-producing peanut-nodulating bacteria[1].
References	[1]. Liu J, et al. Detection of Diverse N-Acyl-Homoserine Lactones in Vibrio alginolyticus and Regulation of Biofilm Formation by N-(3-Oxodecanoyl) Homoserine Lactone In vitro. Front Microbiol. 2017 Jun 16;8:1097.