83729-01-5
83729-01-5 structure
- Name: Salvinorin A(Divinorin A)
- Chemical Name: methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-acetyloxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
- CAS Number: 83729-01-5
- Molecular Formula: C23H28O8
- Molecular Weight: 432.464
- Catalog: analytical chemistry Standard standard material
- Create Date: 2018-08-11 23:08:52
- Modify Date: 2024-01-11 23:13:46
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Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is isolated from Salvia divinorum. Salvinorin A preserves cerebral pial artery autoregulation after forebrain ischemia via the PI3K/AKT/cGMP pathway. Salvinorin A ameliorates cerebral vasospasm through activation of endothelial nitric oxide synthase in a rat model of subarachnoid hemorrhage.
| Name | methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-acetyloxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate |
|---|---|
| Synonyms |
Methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-acetoxy-2-(3-furyl)-6a,10b-dimethyl-4,10-dioxododecahydro-2H-benzo[f]isochromene-7-carboxylate
2H-Naphtho[2,1-c]pyran-7-carboxylic acid, 9-(acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-, methyl ester, (2S,4aR,6aR,7R,9S,10aS,10bR)- methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxododecahydro-2H-benzo[f]isochromene-7-carboxylate Divinorin A salvonorin A 2H-Naphtho[2,1-c]pyran-7-carboxylic acid, 9-(acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-, methyl ester, (2S,4aR,7R,9S,10aS,10bR)- Salvinorin Methyl (2S,4aR,7R,9S,10aS,10bR)-9-acetoxy-2-(3-furyl)-6a,10b-dimethyl-4,10-dioxododecahydro-2H-benzo[f]isochromene-7-carboxylate Salvinorin A MFCD05664742 Diviner's Sage Mexican mint herbal ecstasy |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 563.8±50.0 °C at 760 mmHg |
| Melting Point | 238-240ºC |
| Molecular Formula | C23H28O8 |
| Molecular Weight | 432.464 |
| Flash Point | 294.8±30.1 °C |
| Exact Mass | 432.178406 |
| PSA | 109.11000 |
| LogP | 1.82 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.548 |
| Symbol |
GHS02, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H302 + H312 + H332-H319 |
| Precautionary Statements | P210-P261-P302 + P352 + P312-P304 + P340 + P312-P337 + P313-P403 + P235 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Hazard Codes | F,Xn |
| Risk Phrases | 11-20/21/22-36 |
| Safety Phrases | S22-S24/25 |
| RIDADR | UN 1648 3 / PGII |
| RTECS | QL6127142 |
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83729-01-5 |
| Literature: Journal of the American Chemical Society, , vol. 129, # 29 p. 8968 - 8969 |
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~86%
83729-01-5 |
| Literature: Nozawa, Masato; Suka, Yuhki; Hoshi, Takashi; Suzuki, Toshio; Hagiwara, Hisahiro Organic Letters, 2008 , vol. 10, # 7 p. 1365 - 1368 |
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83729-01-5 |
| Literature: Journal of the American Chemical Society, , vol. 129, # 29 p. 8968 - 8969 |
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83729-01-5 |
| Literature: Journal of the American Chemical Society, , vol. 129, # 29 p. 8968 - 8969 |
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83729-01-5 |
| Literature: Journal of the American Chemical Society, , vol. 129, # 29 p. 8968 - 8969 |
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~%
83729-01-5 |
| Literature: Journal of the American Chemical Society, , vol. 129, # 29 p. 8968 - 8969 |
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83729-01-5 |
| Literature: Journal of the American Chemical Society, , vol. 129, # 29 p. 8968 - 8969 |
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83729-01-5 |
| Literature: Journal of Organic Chemistry, , vol. 49, p. 4716 - 4720 |
| Precursor 4 | |
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| DownStream 1 | |