3541-42-2

3541-42-2 structure

Name: (2E)-3-(2-hydroxyphenyl)prop-2-enal
Chemical Name: 2-hydroxycinnamaldehyde
CAS Number: 3541-42-2
Molecular Formula: C₉H₈O₂
Molecular Weight: 148.16
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-06-11 20:10:44
Modify Date: 2024-01-05 18:38:32
2-Hydroxycinnamaldehyde is a phenylpropanoid that can be isolated from the bark of Cinnamomum cassia. 2-Hydroxycinnamaldehyde inhibits Wnt/β-catenin, STAT3 signaling. 2-Hydroxycinnamaldehyde induces cell apoptosis 2-Hydroxycinnamaldehyde has antitumor and anti-inflammation activities[1][2][3].

Name	2-hydroxycinnamaldehyde
Synonyms	(2E)-3-(2-Hydroxyphenyl)acrylaldehyde Hydroxycinnamaldehyde o-hydroxycinnamaldehyde (2E)-3-(2-hydroxyphenyl)prop-2-enal 2'-hydroxycinnamaldehyde 3-(2-Hydroxyphenyl)acrylaldehyde 2-Propenal, 3-(2-hydroxyphenyl)-, (2E)- 2-Hydroxy-zimtaldehyd 2-hydroxycinnamicaldehyde o-hydroxy-cinnamaldehyd

Description	2-Hydroxycinnamaldehyde is a phenylpropanoid that can be isolated from the bark of Cinnamomum cassia. 2-Hydroxycinnamaldehyde inhibits Wnt/β-catenin, STAT3 signaling. 2-Hydroxycinnamaldehyde induces cell apoptosis 2-Hydroxycinnamaldehyde has antitumor and anti-inflammation activities[1][2][3].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> STAT Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Stem Cell/Wnt >> Wnt Signaling Pathways >> JAK/STAT Signaling >> STAT Research Areas >> Inflammation/Immunology
References	[1]. Lee MA, et al. Antitumor activity of 2-hydroxycinnamaldehyde for human colon cancer cells through suppression of β-catenin signaling. J Nat Prod. 2013 Jul 26;76(7):1278-84. [2]. Yoon YJ, et al. 2'-hydroxycinnamaldehyde inhibits cancer cell proliferation and tumor growth by targeting the pyruvate kinase M2. Cancer Lett. 2018 Oct 10;434:42-55. [3]. Hao Let al. 2'-Hydroxycinnamaldehyde ameliorates imiquimod-induced psoriasiform inflammation by targeting PKM2-STAT3 signaling in mice. Exp Mol Med. 2021 May;53(5):875-884.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 19,191,1985

Hazard Codes	Xn
HS Code	2912499000

HS Code	2912499000
Summary	2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%