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4684-32-6

4684-32-6 structure
4684-32-6 structure
  • Name: Picrinine
  • Chemical Name: Picrinin
  • CAS Number: 4684-32-6
  • Molecular Formula: C20H22N2O3
  • Molecular Weight: 338.400
  • Catalog: Natural product Alkaloid
  • Create Date: 2018-06-17 15:11:39
  • Modify Date: 2024-01-06 12:49:52
  • Picrinine, an akuammiline alkaloid, is isolated from the leaves of Alstonia scholaris. Picrinine exhibits anti-inflammatory activity through inhibition of the 5-lipoxygenase enzyme[1].

Name Picrinin
Synonyms 2H,12H-6,12a-Epoxy-2,7a-methanoindolo[2,3-a]quinolizine-14-carboxylic acid, 3-ethylidene-1,3,4,6,7,12b-hexahydro-, methyl ester, (2R,3E,6S,7aR,12aR,12bS,14R)-
deacetyl-deformopicraline
desacetyldesformopicraline
Methyl (2α,5α,19E)-1,2-dihydro-2,5-epoxyakuammilan-17-oate
Picrinine
vincaridine
2Alpha,5Alpha-Epoxy-1,2-dihydroakuammilan-17-oic acid methyl ester
Description Picrinine, an akuammiline alkaloid, is isolated from the leaves of Alstonia scholaris. Picrinine exhibits anti-inflammatory activity through inhibition of the 5-lipoxygenase enzyme[1].
Related Catalog
Target

5-Lipoxygenase

References

[1]. Smith JM, et, al. Total synthesis of the akuammiline alkaloid picrinine. J Am Chem Soc. 2014 Mar 26;136(12):4504-7.

Density 1.4±0.1 g/cm3
Boiling Point 501.1±50.0 °C at 760 mmHg
Molecular Formula C20H22N2O3
Molecular Weight 338.400
Flash Point 256.9±30.1 °C
Exact Mass 338.163055
PSA 50.80000
LogP 2.49
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.677
Hazard Codes Xi
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