Picrinine

Modify Date: 2025-08-25 20:19:40

Picrinine structure	Common Name	Picrinine
	CAS Number	4684-32-6	Molecular Weight	338.400
	Density	1.4±0.1 g/cm3	Boiling Point	501.1±50.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₂₂N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	256.9±30.1 °C

Use of Picrinine

Picrinine, an akuammiline alkaloid, is isolated from the leaves of Alstonia scholaris. Picrinine exhibits anti-inflammatory activity through inhibition of the 5-lipoxygenase enzyme[1].

Name	Picrinin
Synonym	More Synonyms

Description	Picrinine, an akuammiline alkaloid, is isolated from the leaves of Alstonia scholaris. Picrinine exhibits anti-inflammatory activity through inhibition of the 5-lipoxygenase enzyme[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase
Target	5-Lipoxygenase
References	[1]. Smith JM, et, al. Total synthesis of the akuammiline alkaloid picrinine. J Am Chem Soc. 2014 Mar 26;136(12):4504-7.

Density	1.4±0.1 g/cm3
Boiling Point	501.1±50.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₂N₂O₃
Molecular Weight	338.400
Flash Point	256.9±30.1 °C
Exact Mass	338.163055
PSA	50.80000
LogP	2.49
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.677

Hazard Codes	Xi

2H,12H-6,12a-Epoxy-2,7a-methanoindolo[2,3-a]quinolizine-14-carboxylic acid, 3-ethylidene-1,3,4,6,7,12b-hexahydro-, methyl ester, (2R,3E,6S,7aR,12aR,12bS,14R)-

deacetyl-deformopicraline

desacetyldesformopicraline

Methyl (2α,5α,19E)-1,2-dihydro-2,5-epoxyakuammilan-17-oate

Picrinine

vincaridine

2Alpha,5Alpha-Epoxy-1,2-dihydroakuammilan-17-oic acid methyl ester