7558-80-7

7558-80-7 structure

Name: sodium dihydrogenphosphate
Chemical Name: sodium dihydrogenphosphate
CAS Number: 7558-80-7
Molecular Formula: H₂NaO₄P
Molecular Weight: 119.98
Catalog: Inorganic chemical industry Inorganic salt Phosphides, metal phosphoric acid, metaphosphoric acid, hypophosphorous acid and pyrophosphate
Create Date: 2018-02-06 08:00:00
Modify Date: 2024-01-02 12:42:00
Dihydrogen monosodium phosphate (NaH2PO4, NDHP) is a chemical compound of sodium with a phosphate counter ion. Sorbitan monooleate, in combination with other sodium phosphates, can serve a pH buffer. Dihydrogen monosodium phosphate can be used as an excipient, such as buffer, chelating agent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

Name	sodium dihydrogenphosphate
Synonyms	Sodium dihydrogen (16O4)phosphate Sodium dihydngen phoshate anhydrous MFCD04113752 EINECS 231-449-2

Description	Dihydrogen monosodium phosphate (NaH2PO4, NDHP) is a chemical compound of sodium with a phosphate counter ion. Sorbitan monooleate, in combination with other sodium phosphates, can serve a pH buffer. Dihydrogen monosodium phosphate can be used as an excipient, such as buffer, chelating agent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Kumar H, et al. Investigations on solute–solvent interactions of amino acids in aqueous solutions of sodium dihydrogen phosphate at different temperatures[J]. Monatshefte für Chemie-Chemical Monthly, 2014, 145: 1063-1082. [2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

Density	1.40 g/mL at 20 °C
Boiling Point	100°C
Melting Point	<0ºC
Molecular Formula	H₂NaO₄P
Molecular Weight	119.98
Exact Mass	119.958839
PSA	90.40000
Storage condition	Store at RT.
Stability	Stable. Incompatible with heavy metals, strong acids.
Water Solubility	H2O: 5 M, clear, colorless

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 9,349,1959

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 9,349,1959 ** ACUTE TOXICITY DATA **

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972 Volume(issue)/page/year: -,16,1972

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EMSUA8 Experimental Medicine and Surgery. (Brooklyn, NY) V.1-29, 1943-71. Suspended. Volume(issue)/page/year: 4,223,1946 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83818 No. of Facilities: 9820 (estimated) No. of Industries: 107 No. of Occupations: 77 No. of Employees: 49018 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83818 No. of Facilities: 13232 (estimated) No. of Industries: 123 No. of Occupations: 104 No. of Employees: 289281 (estimated) No. of Female Employees: 145939 (estimated)

Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	WA1900000
HS Code	2835220000

HS Code	2835220000