622785-69-7
622785-69-7 structure
- Name: 2'-Deoxy-2'-fluoro-L-uridine
- Chemical Name: 1-(2-Deoxy-2-fluoro-β-L-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione
- CAS Number: 622785-69-7
- Molecular Formula: C9H11FN2O5
- Molecular Weight: 246.19200
- Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
- Create Date: 2018-06-11 11:44:07
- Modify Date: 2024-01-07 17:56:17
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2'-Deoxy-2'-fluoro-l-uridine is an L-nucleoside compound. 2'-Deoxy-2'-fluoro-l-uridine is a potent, selective viral RNA polymerase inhibitor, thereby inhibiting RNA virus replication[1].
| Name | 1-(2-Deoxy-2-fluoro-β-L-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione |
|---|---|
| Synonyms |
(S)-2-chloro-butyric acid dimethylamide
L-2-Chlor-N,N-dimethyl-butyramid L-2'-deoxy-2'-fluorouridine (S)-2-Chlor-buttersaeure-dimethylamid 2-Chloro-N,N-dimethylbutyramide Butanamide,2-chloro-N,N-dimethyl 2'-fluoro-L-uridine |
| Description | 2'-Deoxy-2'-fluoro-l-uridine is an L-nucleoside compound. 2'-Deoxy-2'-fluoro-l-uridine is a potent, selective viral RNA polymerase inhibitor, thereby inhibiting RNA virus replication[1]. |
|---|---|
| Related Catalog |
| Molecular Formula | C9H11FN2O5 |
|---|---|
| Molecular Weight | 246.19200 |
| Exact Mass | 246.06500 |
| PSA | 104.81000 |
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622785-69-7 |
| Literature: Choi, Yongseok; Li, Ling; Grill, Sue; Gullen, Elizabeth; Lee, Chang Soo; Gumina, Giuseppe; Tsujii, Eisaku; Cheng, Yung-Chi; Chu, Chung K. Journal of Medicinal Chemistry, 2000 , vol. 43, # 13 p. 2538 - 2546 |
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622785-69-7 |
| Literature: NOXXON Pharma AG Patent: US2006/183700 A1, 2006 ; Location in patent: Page/Page column 25; Figure 15 ; |
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~82%
622785-69-7 |
| Literature: Shi, Junxing; Du, Jinfa; Ma, Tianwei; Pankiewicz, Krzysztof W.; Patterson, Steven E.; Tharnish, Phillip M.; McBrayer, Tamara R.; Stuyver, Lieven J.; Otto, Michael J.; Chu, Chung K.; Schinazi, Raymond F.; Watanabe, Kyoichi A. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 5 p. 1641 - 1652 |
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622785-69-7 |
| Literature: Shi, Junxing; Du, Jinfa; Ma, Tianwei; Pankiewicz, Krzysztof W.; Patterson, Steven E.; Hassan, Abdalla E. A.; Tharnish, Phillip M.; McBrayer, Tamara R.; Lostia, Stefania; Stuyver, Lieven J.; Watanabe, Kyoichi A.; Chu, Chung K.; Schinazi, Raymond F.; Otto, Michael J. Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 5-7 p. 875 - 879 |
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622785-69-7 |
| Literature: Shi, Junxing; Du, Jinfa; Ma, Tianwei; Pankiewicz, Krzysztof W.; Patterson, Steven E.; Tharnish, Phillip M.; McBrayer, Tamara R.; Stuyver, Lieven J.; Otto, Michael J.; Chu, Chung K.; Schinazi, Raymond F.; Watanabe, Kyoichi A. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 5 p. 1641 - 1652 |
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622785-69-7 |
| Literature: Shi, Junxing; Du, Jinfa; Ma, Tianwei; Pankiewicz, Krzysztof W.; Patterson, Steven E.; Tharnish, Phillip M.; McBrayer, Tamara R.; Stuyver, Lieven J.; Otto, Michael J.; Chu, Chung K.; Schinazi, Raymond F.; Watanabe, Kyoichi A. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 5 p. 1641 - 1652 |
| Precursor 6 | |
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| DownStream 0 | |