- BioBioPha
- China
- Product Name: Glycoursodeoxycholic acid
- Price: ￥Inquiry/5mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Glycoursodeoxycholic acid
- Price: ￥248.0/20mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: GLYCOURSODEOXYCHOLIC ACID
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: 2-[[(4R)-4-[(3R,5S,7S,10R,13R,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
64480-66-6
64480-66-6 structure
- Name: Glycoursodeoxycholic acid
- Chemical Name: Glycoursodeoxycholic acid
- CAS Number: 64480-66-6
- Molecular Formula: C26H43NO5
- Molecular Weight: 449.62300
- Catalog: Natural product Steroidal compound
- Create Date: 2018-05-22 08:00:00
- Modify Date: 2024-01-02 13:06:17
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Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.In Vitro: The antioxidant compound glycoursodeoxycholic acid (GUDCA) fully abrogates UCB-induced cytochrome c oxidase inhibition and significantly prevents oxidative stress, metabolic alterations, and cell demise[1].GUDCA has shown therapeutic efficacy in neurodegenerative models and diseases. Increased cytosolic SOD1 inclusions were observed in 4 DIV NSC-34/hSOD1(G93A) cells together with decreased mitochondria viability, caspase-9 activation, and apoptosis[2]. Glycoursodeoxycholic acid shows preventive and restorative effects against unconjugated bilirubin -induced blood-brain barrier disruption and damage to human brain microvascular endothelial cells[3].
| Name | Glycoursodeoxycholic acid |
|---|---|
| Synonyms | Glycoursodeoxycholic Acid |
| Description | Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.In Vitro: The antioxidant compound glycoursodeoxycholic acid (GUDCA) fully abrogates UCB-induced cytochrome c oxidase inhibition and significantly prevents oxidative stress, metabolic alterations, and cell demise[1].GUDCA has shown therapeutic efficacy in neurodegenerative models and diseases. Increased cytosolic SOD1 inclusions were observed in 4 DIV NSC-34/hSOD1(G93A) cells together with decreased mitochondria viability, caspase-9 activation, and apoptosis[2]. Glycoursodeoxycholic acid shows preventive and restorative effects against unconjugated bilirubin -induced blood-brain barrier disruption and damage to human brain microvascular endothelial cells[3]. |
|---|---|
| Related Catalog |
| Melting Point | 232-235ºC |
|---|---|
| Molecular Formula | C26H43NO5 |
| Molecular Weight | 449.62300 |
| Exact Mass | 449.31400 |
| PSA | 106.86000 |
| LogP | 3.98500 |
| Storage condition | -20°C Freezer |
| RIDADR | NONH for all modes of transport |
|---|