63546-27-0

63546-27-0 structure
63546-27-0 structure
  • Name: L-Alanine-d3
  • Chemical Name: (2S)-2-amino-3,3,3-trideuteriopropanoic acid
  • CAS Number: 63546-27-0
  • Molecular Formula: C3H4D3NO2
  • Molecular Weight: 92.112
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2018-09-10 18:21:17
  • Modify Date: 2024-01-07 17:43:11
  • L-Alanine-d3 (L-2-Aminopropionic acid-d3) is the deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

Name (2S)-2-amino-3,3,3-trideuteriopropanoic acid
Synonyms MFCD00084107
L-<3,3,3-2H3>alanine
L-(3,3,3-H)Alanine
l-alanine-d3
L-Alanine-3,3,3-d3
L-Alanine-3,3,3-d
alanine-C-d3
Description L-Alanine-d3 (L-2-Aminopropionic acid-d3) is the deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Density 1.2±0.1 g/cm3
Boiling Point 212.9±23.0 °C at 760 mmHg
Melting Point 314.5ºC (dec.)(lit.)
Molecular Formula C3H4D3NO2
Molecular Weight 92.112
Flash Point 82.6±22.6 °C
Exact Mass 92.066505
PSA 63.32000
LogP -0.68
Vapour Pressure 0.1±0.9 mmHg at 25°C
Index of Refraction 1.460
Storage condition 2-8°C
RIDADR NONH for all modes of transport
Precursor  1

DownStream  0