Shanghai Nianxing Industrial Co., Ltd
China
Product Name: D-Alanine-3,3,3-d3
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Purity: 98.0%
Stocking Period: 10 Day
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177614-69-6

177614-69-6 structure

177614-69-6 structure

Name: D-(3,3,3-2H3)Alanine
Chemical Name: d-alanine-3,3,3-d3
CAS Number: 177614-69-6
Molecular Formula: C₃H₄D₃NO₂
Molecular Weight: 92.112
Catalog: Research Areas Others
Create Date: 2018-04-24 08:00:00
Modify Date: 2025-08-27 16:09:17
D-Alanine-d3 ((R)-Alanine-d3) is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

Name	d-alanine-3,3,3-d3
Synonyms	D-Alanine-3,3,3-d D-(3,3,3-H)Alanine

Description	D-Alanine-d3 ((R)-Alanine-d3) is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.
Related Catalog	Research Areas >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Schmieden V, et al. Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol Pharmacol. 1995 Nov;48(5):919-27. [3]. Saitoh T, et al. A novel antagonist, phenylbenzene omega-phosphono-alpha-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. Br J Pharmacol. 1994 Sep;113(1):165-70.

Density	1.2±0.1 g/cm3
Boiling Point	212.9±23.0 °C at 760 mmHg
Melting Point	291ºC (dec.)(lit.)
Molecular Formula	C₃H₄D₃NO₂
Molecular Weight	92.112
Flash Point	82.6±22.6 °C
Exact Mass	92.066505
PSA	63.32000
LogP	-0.68
Vapour Pressure	0.1±0.9 mmHg at 25°C
Index of Refraction	1.460

Precursor 0
DownStream 1
177614-70-9

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