9006-65-9

9006-65-9 structure

Name: Dimethicone
Chemical Name: dimethicone macromolecule
CAS Number: 9006-65-9
Molecular Formula: C₆H₁₈OSi₂
Molecular Weight: 162.37800
Catalog: API Digestive system medication Acid and gastric mucosal protective drugs
Create Date: 2018-02-05 08:00:00
Modify Date: 2024-01-02 19:34:57
Dimethicone is an orally active biochemical assay reagents consisting of a fully methylated linear siloxane polymer whose ends are blocked by trimethylsiloxane units. Dimethicone can lubricate hair and physically block the respiratory system of lice to remove lice. Dimethicone has potential applications in cosmetics and daily cleaning products[1][2][3].

Name	dimethicone macromolecule
Synonyms	Dimethicone

Description	Dimethicone is an orally active biochemical assay reagents consisting of a fully methylated linear siloxane polymer whose ends are blocked by trimethylsiloxane units. Dimethicone can lubricate hair and physically block the respiratory system of lice to remove lice. Dimethicone has potential applications in cosmetics and daily cleaning products[1][2][3].
Related Catalog	Research Areas >> Others
In Vivo	Dimethicone (25% 溶于石油醚；呼吸道给药；单剂量) 在 Wistar 大鼠中显示出生物安全性[3]。 Dimethicone (饮食中含 1%、5% 或 10%；口服；90 d) 在 Sprague-Dawley 大鼠中显示出生物安全性[3]。
References	[1]. Nair B, et al. Final report on the safety assessment of stearoxy dimethicone, dimethicone, methicone, amino bispropyl dimethicone, aminopropyl dimethicone, amodimethicone, amodimethicone hydroxystearate, behenoxy dimethicone, C24-28 alkyl methicone, C30-45 alkyl methicone, C30-45 alkyl dimethicone, cetearyl methicone, cetyl dimethicone, dimethoxysilyl ethylenediaminopropyl dimethicone, hexyl methicone, hydroxypropyldimethicone, stearamidopropyl dimethicone, stearyl dimethicone, stearyl methicone, and vinyldimethicone. Int J Toxicol. 2003;22 Suppl 2:11-35. [2]. Ihde ES, et al. Safety and efficacy of a 100% dimethicone pediculocide in school-age children. BMC Pediatr. 2015 Jun 20;15:70. [3]. Shank P D, et al. Safety Assessment of Dimethicone, Methicone, and Substituted-Methicone Polymers, as Used in Cosmetics[J]. 2020.

Density	1 g/mL at 20 °C
Molecular Formula	C₆H₁₈OSi₂
Molecular Weight	162.37800
Flash Point	121 °C
Exact Mass	162.09000
PSA	9.23000
LogP	2.67280
Vapour Pressure	5 mm Hg ( 20 °C)
Index of Refraction	n20/D 1.406
Storage condition	2~8°C
Stability	Stable. Combustible. Incompatible with strong oxidizing agents, reducing agents, organics, acids, alkalis. Corrodes many metals.
Water Solubility	Practically insoluble in water, very slightly soluble or practically insoluble in anhydrous ethanol, miscible with ethyl acetate, with methyl ethyl ketone and with toluene.