1225451-84-2
1225451-84-2 structure
- Name: SKLB1002
- Chemical Name: 2-(6,7-dimethoxyquinazolin-4-yl)sulfanyl-5-methyl-1,3,4-thiadiazole
- CAS Number: 1225451-84-2
- Molecular Formula: C13H12N4O2S2
- Molecular Weight: 320.390
- Catalog: Biochemical Inhibitor Protein tyrosine kinase
- Create Date: 2017-05-02 15:14:38
- Modify Date: 2025-08-27 16:53:56
-
SKLB1002 is a novel and potent VEGFR-2 inhibitor with an IC50 value of 32 nM.
| Name | 2-(6,7-dimethoxyquinazolin-4-yl)sulfanyl-5-methyl-1,3,4-thiadiazole |
|---|---|
| Synonyms |
SKLB1002-25mg
6,7-Dimethoxy-4-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]quinazoline SKLB1002 Quinazoline, 6,7-dimethoxy-4-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]- S7258 SKLB1002-10mg SKLB1002-5mg SKLB1002-50mg |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 522.4±60.0 °C at 760 mmHg |
| Melting Point | 193 °C |
| Molecular Formula | C13H12N4O2S2 |
| Molecular Weight | 320.390 |
| Flash Point | 269.7±32.9 °C |
| Exact Mass | 320.040161 |
| PSA | 123.56000 |
| LogP | 2.40 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.687 |
| Storage condition | <0°C |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 + P330 |
| Hazard Codes | T+ |
| RIDADR | UN 2811 6.1 / PGIII |