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18457-44-8

18457-44-8 structure
18457-44-8 structure
  • Name: Taxinine B
  • Chemical Name: Taxinine B
  • CAS Number: 18457-44-8
  • Molecular Formula: C37H44O11
  • Molecular Weight: 664.74
  • Catalog: Natural product Moss
  • Create Date: 2017-04-16 13:29:08
  • Modify Date: 2025-08-25 20:23:13
  • Taxinine B is a taxoid that can be isolated from Japanese Yew Taxus Cuspid. Taxinine B inhibits CaCl2-induced depolymerization of microtubule. Taxinine B is useful for overcoming multidrug resistance in tumor cells[1].

Name Taxinine B
Synonyms 2-Propenoic acid, 3-phenyl-, (1S,3S,4aR,5R,6R,11R,12R,12aS)-1,5,11,12-tetrakis(acetyloxy)-1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-9,12a,13,13-tetramethyl-4-methylene-8-oxo-6,10-methanobenzocyclodecen-3-yl ester, (2E)-
(2α,5α,7β,9α,10β)-2,7,9,10-tetrakis(acetyloxy)-13-oxotaxa-4(20),11-dien-5-yl (2E)-3-phenylprop-2-enoate
(2α,5α,7β,9α,10β)-2,7,9,10-Tetraacetoxy-13-oxotaxa-4(20),11-dien-5-yl (2E)-3-phenylacrylate
Description Taxinine B is a taxoid that can be isolated from Japanese Yew Taxus Cuspid. Taxinine B inhibits CaCl2-induced depolymerization of microtubule. Taxinine B is useful for overcoming multidrug resistance in tumor cells[1].
Related Catalog
References

[1]. Juníchi Kobayashi, et al. Taxuspines A ∼ C, new taxoids from Japanese yew Taxus cuspidata inhibiting drug transport activity of P-glycoprotein in multidrug-resistant cells. Tetrahedron. 1994. 50 (25), 7401-7416.

Density 1.2±0.1 g/cm3
Boiling Point 705.4±60.0 °C at 760 mmHg
Molecular Formula C37H44O11
Molecular Weight 664.74
Flash Point 286.7±32.9 °C
Exact Mass 664.288391
PSA 148.57000
LogP 5.60
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.558
Hazard Codes Xi
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