115404-57-4

115404-57-4 structure

Name: niloticin
Chemical Name: Niloticin
CAS Number: 115404-57-4
Molecular Formula: C₃₀H₄₈O₃
Molecular Weight: 456.70
Catalog: Natural product Moss
Create Date: 2018-03-19 08:00:00
Modify Date: 2024-01-05 19:27:29
Niloticin, tetracyclic triterpenoid compound, is a osteoclastogenesis inhibitor. Niloticin shows anti-viral, antioxidative, and mosquitocidal activities. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways[1].

Name	Niloticin
Synonyms	niloticin (13α,14β,17α,20S,23R,24S)-23-Hydroxy-24,25-epoxylanost-7-en-3-one Lanost-7-en-3-one, 24,25-epoxy-23-hydroxy-, (13α,14β,17α,20S,23R,24S)-

Description	Niloticin, tetracyclic triterpenoid compound, is a osteoclastogenesis inhibitor. Niloticin shows anti-viral, antioxidative, and mosquitocidal activities. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> PI3K/Akt/mTOR >> Akt
References	[1]. Xu H, et al. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways. Biomed Pharmacother. 2022 May;149:112902.

Hazard Codes	Xi