54009-54-0
54009-54-0 structure
- Name: 2-hydroxy-1-naphthalaldehyde salicyloylhydrazone
- Chemical Name: 2-hydroxy-N'-[(Z)-(2-oxonaphthalen-1-ylidene)methyl]benzohydrazide
- CAS Number: 54009-54-0
- Molecular Formula: C18H14N2O3
- Molecular Weight: 306.32
- Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
- Create Date: 2017-08-20 02:05:25
- Modify Date: 2024-02-06 09:09:35
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(E/Z)-NSAH is an isoform of NSAH (HY-114503), which is reversible and competitive nonnucleoside ribonucleotide reductase (RR) inhibitor, with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively[1].
| Name | 2-hydroxy-N'-[(Z)-(2-oxonaphthalen-1-ylidene)methyl]benzohydrazide |
|---|---|
| Synonyms |
5,6-benzosalicylidene-salicyloyl hydrazide
Benzoic acid,2-hydroxy-,((2-hydroxy-1-naphthalenyl)methylene)hydrazide 1-(2-hydroxybenzoyl)-2-(2-hydroxynaphthal)hydrazine 2-Hydroxy-1-naphthalaldehyde salicyloylhydrazone 2-hydroxy-1-naphthaldehyde salicyloylhydrazone 2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide 2-hydroxy-N'-((2-hydroxy-naphthalen-1-yl)methylene)benzohydrazide N'-[1-(2-hydroxynaphthyl)ethylidene]-2-hydroxybenzohydrazide 5,6-benzosalicylidene salicyloyl hydrazone HNASH |
| Description | (E/Z)-NSAH is an isoform of NSAH (HY-114503), which is reversible and competitive nonnucleoside ribonucleotide reductase (RR) inhibitor, with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively[1]. |
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| Related Catalog | |
| References |
| Density | 1.4g/cm3 |
|---|---|
| Boiling Point | 526.2ºC at 760 mmHg |
| Molecular Formula | C18H14N2O3 |
| Molecular Weight | 306.32 |
| Flash Point | 272.1ºC |
| Exact Mass | 306.10000 |
| PSA | 81.92000 |
| LogP | 3.22930 |
| Index of Refraction | 1.734 |
| HS Code | 2928000090 |
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|
~80%
54009-54-0 |
| Literature: Liu, Ming-Li; Dou, Jian-Min; Li, Da-Cheng; Wang, Da-Qi; Cui, Jian-Zhong Transition Metal Chemistry, 2012 , vol. 37, # 1 p. 117 - 124 |
| HS Code | 2928000090 |
|---|---|
| Summary | 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |