CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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GV6125000
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CHEMICAL NAME :
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Cyclohexane, methyl-
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CAS REGISTRY NUMBER :
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108-87-2
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LAST UPDATED :
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199712
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DATA ITEMS CITED :
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35
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MOLECULAR FORMULA :
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C7-H14
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MOLECULAR WEIGHT :
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98.21
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WISWESSER LINE NOTATION :
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L6TJ A1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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2250 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,82,1982
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TYPE OF TEST :
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LC50 - Lethal concentration, 50 percent kill
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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41500 mg/m3/2H
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,82,1982
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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4 gm/kg
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TOXIC EFFECTS :
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Gastrointestinal - hypermotility, diarrhea
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REFERENCE :
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JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 25,199,1943
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TYPE OF TEST :
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LC50 - Lethal concentration, 50 percent kill
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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15227 ppm/1H
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TOXIC EFFECTS :
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Behavioral - general anesthetic Behavioral - convulsions or effect on seizure threshold Gastrointestinal - changes in structure or function of salivary glands
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REFERENCE :
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JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 25,323,1943
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TYPE OF TEST :
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LD - Lethal dose
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ROUTE OF EXPOSURE :
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Administration onto the skin
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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>86700 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 25,199,1943 ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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10054 ppm/6H/2W-I
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REFERENCE :
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JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 25,323,1943 *** REVIEWS *** ACGIH TLV-TWA 1610 mg/m3 (400 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 500 ppm (2000 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,162,1971 OSHA PEL (Gen Indu):8H TWA 500 ppm (2000 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 500 ppm (2000 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 500 ppm (2000 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 500 ppm (2000 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 400 ppm (1600 mg/m3) JAN 1993 OEL-BELGIUM:TWA 400 ppm (1610 mg/m3) JAN 1993 OEL-DENMARK:TWA 400 ppm (1600 mg/m3) JAN 1993 OEL-FINLAND:TWA 400 ppm (1600 mg/m3);STEL 500 ppm (2000 mg/m3) JAN 1993 OEL-FRANCE:TWA 400 ppm (1600 mg/m3) JAN 1993 OEL-GERMANY:TWA 500 ppm (2000 mg/m3) JAN 1993 OEL-JAPAN:TWA 400 ppm (1600 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 400 ppm (1600 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 500 ppm (2000 mg/m3) JAN 1993 OEL-POLAND:TWA 500 mg/m3 JAN 1993 OEL-RUSSIA:TWA 400 ppm;STEL 50 mg/m3 JAN 1993 OEL-SWITZERLAND:TWA 400 ppm (1600 mg/m3);STEL 800 ppm JAN 1993 OEL-TURKEY:TWA 500 ppm (2000 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 400 ppm (1600 mg/m3);STEL 500 ppm JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO METHYLCYCLOHEXANE-air:10H TWA 400 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 47030 No. of Facilities: 1733 (estimated) No. of Industries: 11 No. of Occupations: 9 No. of Employees: 6292 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 47030 No. of Facilities: 1175 (estimated) No. of Industries: 12 No. of Occupations: 11 No. of Employees: 10076 (estimated) No. of Female Employees: 14 (estimated)
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