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70142-34-6

70142-34-6 structure
70142-34-6 structure
  • Name: Polyoxyl 15 hydroxystearate
  • Chemical Name: 11-hydroxy-17-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]heptadecanoic acid
  • CAS Number: 70142-34-6
  • Molecular Formula: C47H94O19
  • Molecular Weight: 963.23800
  • Catalog: Research Areas Others
  • Create Date: 2018-06-16 17:53:38
  • Modify Date: 2024-01-03 18:08:32
  • Polyoxyl 15 hydroxystearate is a nonionic surfactant and emulsifier. Polyoxyl 15 hydroxystearate is used for improving the solubility and dissolution of poorly watersoluble drugs[1][2].
Name 11-hydroxy-17-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]heptadecanoic acid
Synonyms Polyethylene glycol (15)-hydroxystearate
Polyoxyethylated 12-hydroxystearic acid
Macrogol (15)-hydroxystearate
Description Polyoxyl 15 hydroxystearate is a nonionic surfactant and emulsifier. Polyoxyl 15 hydroxystearate is used for improving the solubility and dissolution of poorly watersoluble drugs[1][2].
Related Catalog
In Vitro Polyoxyl 15 hydroxystearate is found to be effective in enhancing the solubility and stability of Curcumin (HY-N0005)[2]. Polyoxyl 15 hydroxystearate is employed as a carrier to build up a stable CoQ10-loaded micelle delivery system[3].
References

[1]. Cho HJ, et al. Poly(lactic-co-glycolic) Acid/Solutol HS15-Based Nanoparticles for Docetaxel Delivery. J Nanosci Nanotechnol. 2016;16(2):1433‐1436.

[2]. Seo SW, et al. Preparation and pharmacokinetic evaluation of curcumin solid dispersion using Solutol® HS15 as a carrier. Int J Pharm. 2012;424(1-2):18‐25.

[3]. Liu L, et al. Kolliphor® HS 15 Micelles for the Delivery of Coenzyme Q10: Preparation, Characterization, and Stability. AAPS PharmSciTech. 2016;17(3):757-766.
Density 1.048 g/cm3 at 20 °C
Melting Point 25-30 °C
Molecular Formula C47H94O19
Molecular Weight 963.23800
Flash Point 272 ℃
Exact Mass 962.63900
PSA 216.21000
LogP 4.13460
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H317
Precautionary Statements P280
Hazard Codes Xi
Safety Phrases 24-37
RIDADR NONH for all modes of transport
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