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859502-43-5

859502-43-5 structure
859502-43-5 structure
  • Name: GR 125487 sulfamate
  • Chemical Name: Sulfamic acid-(1-{2-[(methylsulfonyl)amino]ethyl}-4-piperidinyl )methyl 5-fluoro-2-methoxy-1H-indole-3-carboxylate (1:1)
  • CAS Number: 859502-43-5
  • Molecular Formula: C19H29FN4O8S2
  • Molecular Weight: 524.58
  • Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
  • Create Date: 2016-09-19 04:57:23
  • Modify Date: 2023-04-04 21:46:57
  • GR125487 sulfamate is an orally active and selective antagonist of 5-HT4R. GR125487 sulfamate effectively blocks the cognition enhancing effect. GR125487 sulfamate can be used to study memory disorders, gastrointestinal disorders, mood disorders and urinary tract dysfunction[1].

Name Sulfamic acid-(1-{2-[(methylsulfonyl)amino]ethyl}-4-piperidinyl )methyl 5-fluoro-2-methoxy-1H-indole-3-carboxylate (1:1)
Synonyms [Ala92]-p16 (84-103)
Description GR125487 sulfamate is an orally active and selective antagonist of 5-HT4R. GR125487 sulfamate effectively blocks the cognition enhancing effect. GR125487 sulfamate can be used to study memory disorders, gastrointestinal disorders, mood disorders and urinary tract dysfunction[1].
Related Catalog
References

[1]. Nirogi, R., et al. Synthesis of GR 125487, a selective 5-HT4receptor antagonist. Synthetic Communications, 46(12), 1036–1043.

Molecular Formula C19H29FN4O8S2
Molecular Weight 524.58
Exact Mass 524.14100
PSA 197.88000
LogP 3.67220