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161923-50-8

161923-50-8 structure
161923-50-8 structure
  • Name: 6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
  • Chemical Name: 6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
  • CAS Number: 161923-50-8
  • Molecular Formula: C16H17ClN4O8
  • Molecular Weight: 428.78
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2017-11-15 19:39:41
  • Modify Date: 2024-04-03 21:19:08
  • 6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name 6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
Synonyms 6-chloropyrazine-2-ylhydrazine
2-chloro-6-hydrazinopyridazine
2-Hydrazino-6-chlorpyrazin
2-Chloro-6-hydrazinylpyrazine
2',3',5'-triacetyl-6-chloroguanosine
6-chloro-2-hydrazinopyrazine
2-chloro-6-hydrazino-pyrazine
Description 6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Molecular Formula C16H17ClN4O8
Molecular Weight 428.78
Exact Mass 428.07300
PSA 151.96000
LogP 0.50920
Index of Refraction 1.678

~97%

161923-50-8 structure

161923-50-8

Literature: Moorman, Allan R. Patent: US2003/199686 A1, 2003 ; Location in patent: Page/Page column 6 ;
Precursor  1

DownStream  1