DC Chemicals Limited
China
Product Name: Aβ42 agonist-2
Price: ￥550.0/100mg ￥850.0/250mg ￥1800.0/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Benzo[b]thiophene-2-carboxamide,N-phenyl-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

6314-40-5

6314-40-5 structure

Name: Benzo[b]thiophene-2-carboxamide,N-phenyl-
Chemical Name: N-phenyl-1-benzothiophene-2-carboxamide
CAS Number: 6314-40-5
Molecular Formula: C₁₅H₁₁NOS
Molecular Weight: 253.31900
Catalog: Research Areas Neurological Disease
Create Date: 2017-08-28 18:41:47
Modify Date: 2025-08-22 18:12:51
Aβ42 agonist-2 (compound 7b) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-2 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-2 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells[1].

Name	N-phenyl-1-benzothiophene-2-carboxamide
Synonyms	benzo[b]thiophene-2-carboxylic acid anilide benzothiophene-2-carboxanilide HMS3078J06 Benzo[b]thiophen-2-carbonsaeure-anilid Benzo[b]thiophene-2-carboxanilide 2-Benzo<b>thenoyl-anilid N-phenylbenzo[b]thiophene-2-carboxamide

Description	Aβ42 agonist-2 (compound 7b) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-2 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-2 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells[1].
Related Catalog	Research Areas >> Neurological Disease
Target	Aβ42 aggregation[1]
References	[1]. Zhao Y et al. Small Molecules N-Phenylbenzofuran-2-carboxamide and N-Phenylbenzo[b]thiophene-2-carboxamide Promote Beta-Amyloid (Aβ42) Aggregation and Mitigate Neurotoxicity. ACS Chem Neurosci. 2023 Nov 16.

Density	1.32g/cm3
Boiling Point	346.2ºC at 760 mmHg
Molecular Formula	C₁₅H₁₁NOS
Molecular Weight	253.31900
Flash Point	163.1ºC
Exact Mass	253.05600
PSA	57.34000
LogP	4.22660
Index of Refraction	1.735

HS Code	2934999090

6314-28-9

74497-02-2

~71%

6314-40-5

Literature: Antonow, Dyeison; Marrafa, Teresa; Dawood, Irfaan; Ahmed, Tauheed; Haque, Mohammad R.; Thurston, David E.; Zinzalla, Giovanna Chemical Communications, 2010 , vol. 46, # 13 p. 2289 - 2291

39827-11-7

74497-02-2

6314-40-5

Literature: Goettsch; Wiese Journal of the American Pharmaceutical Association (1912-1977), 1958 , vol. 47, p. 319,320

95-15-8

6314-40-5

Literature: Shirley; Cameron Journal of the American Chemical Society, 1952 , vol. 74, p. 664

Precursor 3
6314-28-9 39827-11-7 95-15-8
DownStream 0

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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