67247-11-4

67247-11-4 structure

Name: For-Met-Leu-Phe-Lys-OH
Chemical Name: N-Formyl-L-methionyl-L-leucyl-L-phenylalanyl-L-lysine
CAS Number: 67247-11-4
Molecular Formula: C₂₇H₄₃N₅O₆S
Molecular Weight: 565.73
Catalog: Research Areas Others
Create Date: 2018-12-13 12:26:48
Modify Date: 2024-01-10 11:13:20
N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively[1].

Name	N-Formyl-L-methionyl-L-leucyl-L-phenylalanyl-L-lysine
Synonyms	L-Lysine,N-formyl-L-methionyl-L-leucyl-L-phenylalanyl (2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]hexanoic acid FOR-MET-LEU-PHE-LYS-OH FOR-MET-LEU-PHE-LYS N-Formyl-Met-Leu-Phe-Lys

Description	N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	EC50: 3.5 nM (FPR1), 6.7 μM (FPR2), 0.88 μM (FPR2-D2817.32G)[1]
References	[1]. He HQ, et al. Structural determinants for the interaction of formyl peptide receptor 2 with peptide ligands. J Biol Chem. 2014 Jan 24;289(4):2295-306.