Name | roburic acid |
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Synonyms |
1-chrysenepropanoic acid, 1,2,3,4,4a,4b,5,6,6a,7,8,9,10,10a,12,12a-hexadecahydro-1,4a,4b,6a,9,10-hexamethyl-2-(1-methylethenyl)-, (1S,2S,4aR,4bS,6aR,9R,10S,10aR,12aR)-
3-[(1S,2S,4aR,4bS,6aR,9R,10S,10aR,12aR)-1,4a,4b,6a,9,10-Hexamethyl-2-(prop-1-en-2-yl)-1,2,3,4,4a,4b,5,6,6a,7,8,9,10,10a,12,12a-hexadecahydrochrysen-1-yl]propanoic acid Roburinsaeure 3-[(1S,2S,4aR,4bS,6aR,9R,10S,10aR,12aR)-2-Isopropenyl-1,4a,4b,6a,9,10-hexamethyl-1,2,3,4,4a,4b,5,6,6a,7,8,9,10,10a,12,12a-hexadecahydro-1-chrysenyl]propanoic acid Roburic Acid Robursaeure |
Description | Roburic acid, a tetracyclic triterpenoid found in Gentiana macrophylla, acts as an inhibitor of COX, with IC50s of 5 and 9 μM for COX-1 and COX-2, respectively[1]. |
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Related Catalog | |
Target |
COX-1:5 μM (IC50) COX-2:9 μM (IC50) |
References |
Density | 1.0±0.1 g/cm3 |
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Boiling Point | 528.5±49.0 °C at 760 mmHg |
Molecular Formula | C30H48O2 |
Molecular Weight | 440.701 |
Flash Point | 424.9±25.0 °C |
Exact Mass | 440.365417 |
PSA | 37.30000 |
LogP | 11.09 |
Vapour Pressure | 0.0±3.0 mmHg at 25°C |
Index of Refraction | 1.532 |
Safety Phrases | 24/25 |
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~% 6812-81-3 |
Literature: Gazzetta Chimica Italiana, , vol. 94, p. 382 - 392 |