70904-56-2

70904-56-2 structure

Name: Kyotorphin acetate salt
Chemical Name: L-tyrosyl-L-arginine
CAS Number: 70904-56-2
Molecular Formula: C₁₅H₂₃N₅O₄
Molecular Weight: 337.37400
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-06-17 13:08:04
Modify Date: 2024-01-10 18:34:01
Kyotorphin is an endogenou neuroactive dipeptide with analgesic properties. Kyotorphin possesses anti-inflammatory and antimicrobial activity. Kyotorphin levels in cerebro-spinal fluid correlate negatively with the progression of neurodegeneration in Alzheimer's Disease patients[1].

Name	L-tyrosyl-L-arginine
Synonyms	D-Kyotorphin Tyr-arg L-Arginine,N2-L-tyrosyl L-Tyr-L-Arg L-Araginine,L-tyrosyl kyotorphin Arginine,N2-tyrosyl Kiotorphin L-Tyrosyl-L-arginine (2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid

Description	Kyotorphin is an endogenou neuroactive dipeptide with analgesic properties. Kyotorphin possesses anti-inflammatory and antimicrobial activity. Kyotorphin levels in cerebro-spinal fluid correlate negatively with the progression of neurodegeneration in Alzheimer's Disease patients[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	The analgesic effect of kyotorphin is determined by means of the hot-plate test, with an ED50 value of 5.3 μg/animal (15.7 nmole/animal)[1].
References	[1]. Takagi H, et al. Morphine-like analgesia by a new dipeptide, L-tyrosyl-L-arginine (Kyotorphin) and its analogue. Eur J Pharmacol. 1979;55(1):109-111.