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110-27-0

110-27-0 structure
110-27-0 structure
  • Name: Isopropyl myristate
  • Chemical Name: Isopropyl myristate
  • CAS Number: 110-27-0
  • Molecular Formula: C17H34O2
  • Molecular Weight: 270.451
  • Catalog: Surfactant Nonionic surfactant Polyol ester type
  • Create Date: 2018-07-10 20:10:42
  • Modify Date: 2025-08-20 18:42:39
  • Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid. Isopropyl myristate (IPM) is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired[1].
Name Isopropyl myristate
Synonyms Tetradecanoic acid, isopropyl ester
Isomyst
Tetradecanoic acid 1-methylethyl ester
IPM
Revenge
Tetradecanoic acid isopropyl ester
myristic acid isopropyl ester
IPM 100,IPM-EX,IPM-R
BISOMEL
Propan-2-yl tetradecanoate
ESTERGEL
MFCD00008982
13VOY1&1
Tetradecanoic acid, 1-methylethyl ester
1-methylethyl ester of tetradecanoic acid
Promyr
Isopropyl-myristate
D 50
i-propyl myristate
Emcol-IM
Isopropyl myristate
isopropyl tetradecanoate
1-Methylethyl tetradecanoate
Myristic acid, isopropyl ester
ja-faipm
EINECS 203-751-4
Tegester
isopropyl myristinate
Description Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid. Isopropyl myristate (IPM) is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired[1].
Related Catalog
References

[1]. Engelbrecht, T, et al. (2012). Study of the influence of the penetration enhancer isopropyl myristate on the nanostructure of stratum corneum lipid model membranes using neutron diffraction and deuterium labelling. Skin Pharmacol Physiol, 25:200-7
Density 0.9±0.1 g/cm3
Boiling Point 319.9±0.0 °C at 760 mmHg
Melting Point -5°C
Molecular Formula C17H34O2
Molecular Weight 270.451
Flash Point 144.1±8.8 °C
Exact Mass 270.255890
PSA 26.30000
LogP 7.43
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.440
Storage condition 2-8°C
Stability Stable. Combustible. Incompatible with strong oxidizing agents.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XB8600000
CHEMICAL NAME :
Tetradecanoic acid, isopropyl ester
CAS REGISTRY NUMBER :
110-27-0
BEILSTEIN REFERENCE NO. :
1781127
LAST UPDATED :
199710
DATA ITEMS CITED :
17
MOLECULAR FORMULA :
C17-H34-O2
MOLECULAR WEIGHT :
270.51
WISWESSER LINE NOTATION :
13VOY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Human
REFERENCE :
85DKA8 "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill, V.A., and P. Lazar, eds., New York, Academic Press, Inc. 1977 Volume(issue)/page/year: -,127,1977
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
REFERENCE :
CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 19,276,1971
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
REFERENCE :
CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>16 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(2),247,1990
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>41 gm/m3/1H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 11,43,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>79500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(2),247,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
49700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(2),247,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>50200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(2),247,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(2),247,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
>25 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2703360 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81855 No. of Facilities: 2668 (estimated) No. of Industries: 26 No. of Occupations: 30 No. of Employees: 108035 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81855 No. of Facilities: 5230 (estimated) No. of Industries: 24 No. of Occupations: 51 No. of Employees: 113871 (estimated) No. of Female Employees: 61855 (estimated)
Personal Protective Equipment Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany -
RTECS XB8600000
Packaging Group I; II; III
Hazard Class 6.1
HS Code 29159080
544-63-8 structure

544-63-8

67-63-0 structure

67-63-0

~93%

110-27-0 structure

110-27-0

Literature: Sanna, Vanna; Mariani, Alberto; Caria, Giuseppe; Sechi, Mario Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 7 p. 680 - 684
94-36-0 structure

94-36-0

~%

110-27-0 structure

110-27-0

Literature: US2012/252897 A1, ;
67-63-0 structure

67-63-0

112-64-1 structure

112-64-1

~%

110-27-0 structure

110-27-0

Literature: Journal of the American Oil Chemists' Society, , vol. 24, p. 257
HS Code 2915900090
Summary 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%
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