153086-78-3

153086-78-3 structure

Name: N-BOC-2,2′-(ethylenedioxy)bis(ethylamine)
Chemical Name: tert-butyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]carbamate
CAS Number: 153086-78-3
Molecular Formula: C₁₁H₂₄N₂O₄
Molecular Weight: 248.319
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-11-24 17:52:29
Modify Date: 2024-01-02 22:20:17
PROTAC Linker 13 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 13 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name	tert-butyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]carbamate
Synonyms	CBZ-L-Asginine-OH Hydrochloride AmbotzBNN1016 2-Methyl-2-propanyl {2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamate N-BOC-2,2′-(ethylenedioxy)bis(ethylamine) Carbamic acid, N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-, 1,1-dimethylethyl ester N-Boc-3,6-dioxa-1,8-octanediamine N-Boc-3,6-dioxaoctane-1,8-diamine t-Boc-N-amido-PEG2-Amine

Description	PROTAC Linker 13 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 13 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Personal Protective Equipment	Eyeshields;Gloves
RIDADR	NONH for all modes of transport
WGK Germany	3