Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3-(Phenylazo)-2,6-pyridinediamine
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Purity: 98.0%
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94-78-0

94-78-0 structure

Name: 3-(Phenylazo)-2,6-pyridinediamine
Chemical Name: phenazopyridine
CAS Number: 94-78-0
Molecular Formula: C₁₁H₁₁N₅
Molecular Weight: 213.23900
Catalog: API Urinary system medication Diuretic
Create Date: 2018-09-19 19:11:54
Modify Date: 2024-01-03 11:04:59
Phenazopyridine has a local analgesic effect on the urinary tract, often used to alleviate the pain, irritation, discomfort, or urgency caused by urinary tract infections, surgery, or injury to the urinary tract[1].

Name	phenazopyridine
Synonyms	Baridium Pyridium 3-Phenylazo-pyridin-2,6-diyldiamin Viridium 2,6-diamino-3-(phenylazo)pyridine Sedural Pyridiate Gastracid Urodine 3-phenylazo-pyridine-2,6-diamine Urogesic Geridium 3-phenyldiazenylpyridine-2,6-diamine

Description	Phenazopyridine has a local analgesic effect on the urinary tract, often used to alleviate the pain, irritation, discomfort, or urgency caused by urinary tract infections, surgery, or injury to the urinary tract[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Norris RD, et al. A prospective, randomized, double-blinded placebo-controlled comparison of extended release oxybutynin versus phenazopyridine for the management of postoperative ureteral stent discomfort. Urology. 2008 May;71(5):792-5.

Density	1.32g/cm3
Boiling Point	442.3ºC at 760mmHg
Melting Point	235 - 240ºC
Molecular Formula	C₁₁H₁₁N₅
Molecular Weight	213.23900
Exact Mass	213.10100
PSA	89.65000
LogP	3.82380
Index of Refraction	1.6880 (estimate)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US7700000

CHEMICAL NAME :: Pyridine, 2,6-diamino-3-(phenylazo)-

CAS REGISTRY NUMBER :: 94-78-0

BEILSTEIN REFERENCE NO. :: 0184497

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C11-H11-N5

MOLECULAR WEIGHT :: 213.27

WISWESSER LINE NOTATION :: T6NJ BZ CNUNR& FZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 560 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 51,200,1934

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 580 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PAHEAA Pharmaceutica Acta Helvetiae. (Schweizerische Apothekerzeitung, Postfach 3006, CH3000 Bern, 7, Switzerland) V.1- 1926- Volume(issue)/page/year: 35,423,1960 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - tumors

REFERENCE :: BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 11,212,1957 *** REVIEWS *** IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,117,1975 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,117,1975 TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971

Hazard Codes	Xi
HS Code	2933399090

136-40-3

~91%

94-78-0

Literature: PINNACLE PHARMACEUTICALS, INC.; HECHT, Sidney; FAHMI, Nour, Eddine; ROY, Samir, D.; BONNEVILLE, George Patent: WO2010/71878 A1, 2010 ; Location in patent: Page/Page column 39-40 ;

100-34-5

94-78-0

Literature: Tschitschibabin; Seide Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1920 , vol. 50, p. 528 Chem. Zentralbl., 1923 , vol. 94, # III p. 1022

Precursor 2
136-40-3 100-34-5
DownStream 2
4318-79-0 29817-76-3

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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