27314-97-2
27314-97-2 structure
- Name: Tirapazamine
- Chemical Name: tirapazamine
- CAS Number: 27314-97-2
- Molecular Formula: C7H6N4O2
- Molecular Weight: 178.148
- Catalog: Research Areas Cancer
- Create Date: 2018-07-04 15:46:40
- Modify Date: 2025-08-20 18:02:07
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Tirapazamine is an anticancer agent that shows selective cytotoxicity for hypoxic cells in solid tumors, thereby inducing single-and double-strand breaks in DNA, base damage, and cell death.
| Name | tirapazamine |
|---|---|
| Synonyms |
4-hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine
1,2,4-Benzotriazin-3-amine, 1,4-dioxide 3-Amino-1,2,4-benzotriazine 1,4-Dioxide 1,4-Dioxido-1,2,4-benzotriazin-3-ylamine SR 259075 1,2,4-Benzotriazin-3-amine 1,4-dioxide 4-Hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine SR 259075 SR 4233 Tirazone Win 59075 Tirazone Tirapazamine 3-Aminobenzo[e][1,2,4]triazine 1,4-dioxide |
| Description | Tirapazamine is an anticancer agent that shows selective cytotoxicity for hypoxic cells in solid tumors, thereby inducing single-and double-strand breaks in DNA, base damage, and cell death. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 493.6±28.0 °C at 760 mmHg |
| Melting Point | 220ºC |
| Molecular Formula | C7H6N4O2 |
| Molecular Weight | 178.148 |
| Flash Point | 252.3±24.0 °C |
| Exact Mass | 178.049072 |
| PSA | 89.83000 |
| LogP | -0.31 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.777 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
|
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
| RTECS | DM0671500 |
| Precursor 6 | |
|---|---|
| DownStream 3 | |
