21730-93-8

21730-93-8 structure
21730-93-8 structure
  • Name: L-threonolactone
  • Chemical Name: L-threonolactone
  • CAS Number: 21730-93-8
  • Molecular Formula: C4H6O4
  • Molecular Weight: 118.09
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2017-12-19 01:45:06
  • Modify Date: 2024-02-01 17:10:11
  • L-Threonolactone ((3R,4S)-3,4-Dihydroxyoxolan-2-one) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name L-threonolactone
Synonyms 2,3-dihydroxydihydrofuran-1-one
Threonolactone
di-TMS-Threono-1,4-lactone
(3R,4S)-3,4-Dihydroxydihydrofuran-2(3H)-one
L-threonic acid-4-lactone
threonic acid-1,4-lactone
L-treono-1,4-lactone
L-Threonic acid-1,4-lactone
(3R,4S)-3,4-dihydroxyoxolan-2-one
Bis-TMS-Threono-1,4-lactone
L-Threonsaeure-4-lacton
(3R,4S)-3,4-dihydroxy-dihydrofuran-2-one
Description L-Threonolactone ((3R,4S)-3,4-Dihydroxyoxolan-2-one) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 0.99g/cm3
Boiling Point 277.8ºC at 760mmHg
Molecular Formula C4H6O4
Molecular Weight 118.09
Flash Point 101.3ºC
Exact Mass 118.02700
PSA 66.76000
Vapour Pressure 0.00443mmHg at 25°C
Index of Refraction 1.437
RIDADR NONH for all modes of transport
HS Code 2932209090
Precursor  0

DownStream  1

HS Code 2932209090
Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%