115388-96-0

115388-96-0 structure

Name: H-D-Phe-Pip-Arg-pNA acetate
Chemical Name: d-phe-pip-arg-pna
CAS Number: 115388-96-0
Molecular Formula: C₂₇H₃₆N₈O₅
Molecular Weight: 552.62500
Catalog: Research Areas Others
Create Date: 2017-04-09 07:07:51
Modify Date: 2024-01-05 11:30:47
H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform[1][2].

Name	d-phe-pip-arg-pna
Synonyms	D-PHE-L-PIPECOLYL-ARG P-NITROANILIDE*TRI ACETATE D-Phe-L-pipecolyl-Arg-p-nitroanilide dihydrochloride Thrombin Substrate Chromogenix S-2765

Description	H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Goodnight SH Jr, et al. Measurement of antithrombin III in normal and pathologic states using chromogenic substrate S-2238. Comparison with immunoelectrophoretic and factor Xa inhibition assays. Am J Clin Pathol. 1980;73(5):639-647. [2]. Voorthuizen H, Kluft C. Improved assay conditions for automated antithrombin III determinations with the chromogenic substrate S-2238. Thromb Haemost. 1984;52(3):350-353.