BioBioPha
China
Product Name: 7,8-Benzoflavone
Price: ￥Inquiry/50mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 7,8-Benzoflavone
Price: ￥138.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: 7,8-Benzoflavone
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: alpha-Naphthoflavone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

604-59-1

604-59-1 structure

604-59-1 structure

Name: 7,8-Benzoflavone
Chemical Name: α-naphthoflavone
CAS Number: 604-59-1
Molecular Formula: C₁₉H₁₂O₂
Molecular Weight: 272.297
Catalog: Biochemical Biochemical reagent Acid-base indicator
Create Date: 2018-03-14 08:00:00
Modify Date: 2024-01-02 17:46:03
Alpha-Naphthoflavone is a synthetic flavonoid, acts as a potent and competitive aromatase inhibitor with an IC50 and a Ki of 0.5 and 0.2 μM, respectively[1].

Name	α-naphthoflavone
Synonyms	Benzo[h]flavone 2-phenylbenzo[h]chromen-4-one 4H-Naphtho[1,2-b]pyran-4-one, 2-phenyl- α-Naphthylflavone 2-Phenyl-4H-benzo[h]chromen-4-one 2-Phenylbenzo(h)chromen-4-one a-Naphthylflavone 2-Phenyl-benzo[h]chromen-4-one alpha-naphthoflavone 7,8-Benzoflavone MFCD00004985 a-Naphthoflavone α-Naphthoflavone 2-Phenyl-4H-naphtho[1,2-b]pyran-4-one EINECS 210-071-1

Description	Alpha-Naphthoflavone is a synthetic flavonoid, acts as a potent and competitive aromatase inhibitor with an IC50 and a Ki of 0.5 and 0.2 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Aromatase
Target	IC50: 0.5 μM (Aromatase)[1] Ki: 0.2 μM (Aromatase)[1]
References	[1]. Campbell DR, et al. Flavonoid inhibition of aromatase enzyme activity in human preadipocytes. J Steroid Biochem Mol Biol. 1993 Sep;46(3):381-8.

Density	1.3±0.1 g/cm3
Boiling Point	460.9±45.0 °C at 760 mmHg
Melting Point	153-157 °C(lit.)
Molecular Formula	C₁₉H₁₂O₂
Molecular Weight	272.297
Flash Point	215.8±22.3 °C
Exact Mass	272.083740
PSA	30.21000
LogP	4.79
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.695
Storage condition	2-8°C
Stability	Stable. Incompatible with strong oxidizing agents.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QL6250000

CHEMICAL NAME :: 4H-Naphtho(1,2-b)pyran-4-one, 2-phenyl-

CAS REGISTRY NUMBER :: 604-59-1

BEILSTEIN REFERENCE NO. :: 0210862

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C19-H12-O2

MOLECULAR WEIGHT :: 272.31

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 40 umol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 47,3662,1987

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi,Xn,C,F
Risk Phrases	68-34-11
Safety Phrases	S24/25-S36/37
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	QL6250000
HS Code	2914399090

Precursor 0
DownStream 1
65-85-0

HS Code	2914399090
Summary	2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%