580-22-3

580-22-3 structure

Name: 2-Aminoquinoline
Chemical Name: 2-Aminoquinoline
CAS Number: 580-22-3
Molecular Formula: C₉H₈N₂
Molecular Weight: 144.17
Catalog: Pharmaceutical intermediate Heterocyclic compound Quinoline compound
Create Date: 2018-07-30 14:15:18
Modify Date: 2024-01-02 14:06:38
2-Aminoquinoline is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents[1].

Name	2-Aminoquinoline
Synonyms	MFCD00038079 2(1H)-Quinolinimine 2-Aminoquindine EINECS 209-458-8 2-Quinolinamine iminoquinoline quinolin-2-amine

Description	2-Aminoquinoline is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Neurological Disease
References	[1]. Pensa AV, et al. Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J Med Chem. 2017;60(16):7146-7165.

REFERENCE :: ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 42,861,1978

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H302-H315-H318-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Hazard Codes	Xn: Harmful;
Risk Phrases	R20/21/22;R36/37/38
Safety Phrases	S26-S36/37/39-S22
RIDADR	NONH for all modes of transport
RTECS	VA9621800
HS Code	2933499090

HS Code	2933499090
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%