Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Aminobenzenesulfonamide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: 2-Aminobenzenesulfonamide
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

3306-62-5

3306-62-5 structure

Name: 2-Aminobenzenesulfonamide
Chemical Name: 2-Aminobenzenesulfonamide
CAS Number: 3306-62-5
Molecular Formula: C₆H₈N₂O₂S
Molecular Weight: 172.205
Catalog: Organic raw materials Amino compound Amide compound
Create Date: 2018-02-20 08:00:00
Modify Date: 2024-01-07 12:54:14
2-Aminobenzenesulfonamide is a carbonic anhydrase IX inhibitor.

Name	2-Aminobenzenesulfonamide
Synonyms	2-Aminobenzenesulfonamide orthanilamide aminobenzenesulfonamide 2-Sulphamoylaniline EINECS 221-988-1 MFCD08443599 sulfamoylaniline o-sulfanilamide 2-amino-benzenesulfonamid Benzenesulfonamide, 2-amino- o-amino-benzenesulfonamid 2-Aminobenzenesulfonamde 2-Amino-Benzensulfonamide o-aminobenzenesulfonamide 2-Aminobenzenesulfamide

Description	2-Aminobenzenesulfonamide is a carbonic anhydrase IX inhibitor.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase Research Areas >> Cancer
Target	carbonic anhydrase IX[1]
References	[1]. Vullo D, et al. Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1005-9.

Density	1.4±0.1 g/cm3
Boiling Point	392.7±44.0 °C at 760 mmHg
Melting Point	155-157 °C(lit.)
Molecular Formula	C₆H₈N₂O₂S
Molecular Weight	172.205
Flash Point	191.3±28.4 °C
Exact Mass	172.030655
PSA	94.56000
LogP	0.22
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.628

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DA9449000

CHEMICAL NAME :: Benzenesulfonamide, o-amino-

CAS REGISTRY NUMBER :: 3306-62-5

BEILSTEIN REFERENCE NO. :: 0512329

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H8-N2-O2-S

MOLECULAR WEIGHT :: 172.22

WISWESSER LINE NOTATION :: ZSWR BZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 10,319,1937 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84518 No. of Facilities: 28 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 168 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S36/37/39-S26-S22
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	DA9449000
HS Code	2935009090

5455-59-4

~90%

3306-62-5

Literature: Ismail, Mohamed A.H.; Abou El Ella, Dalal A.; Abouzid, Khaled A.M.; Mahmoud, Amr H. Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 17 p. 5647 - 5647

107342-23-4

3306-62-5

Literature: US4806640 A1, ;

13338-00-6

3306-62-5

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 14 p. 3833 - 3838

1694-92-4

121-51-7

3306-62-5

Literature: US4976773 A1, ;

50881-48-6

3306-62-5

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 14 p. 3833 - 3838

74497-02-2

3306-62-5

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 14 p. 3833 - 3838

6961-82-6

3306-62-5

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 14 p. 3887 - 3890

1694-92-4

3306-62-5

Literature: Bioorganic and Medicinal Chemistry, , vol. 20, # 7 p. 2455 - 2478

13338-00-6

74497-02-2

3306-62-5

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. <2> 95, p. 393

Precursor 7
5455-59-4 107342-23-4 13338-00-6 1694-92-4
121-51-7 50881-48-6 6961-82-6
DownStream 10
54734-84-8 21639-28-1 20896-44-0 364-98-7
88-21-1 359-85-3 360-80-5 14141-71-0
$9-methyl-10,10-dioxo-10$l^{6}-thia-7,9-diazabicyclo[4.4.0]deca-1,3,5-trien-8-one structure$ 13514-00-6 13338-00-6

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

3306-62-5	17800-60-1
54773-54-5	54734-81-5
54734-85-9	240139-71-3
194020-05-8	5790-69-2
57947-01-0	761435-31-8