171596-43-3

171596-43-3 structure

Name: (1S,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester
Chemical Name: Methyl (1S,3S)-1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-β-c arboline-3-carboxylate
CAS Number: 171596-43-3
Molecular Formula: C₂₀H₁₈N₂O₄
Molecular Weight: 350.36800
Create Date: 2017-11-27 01:24:35
Modify Date: 2024-01-02 21:07:54

Name	Methyl (1S,3S)-1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-β-c arboline-3-carboxylate
Synonyms	trans-3-Aminocyclopentanecarboxylic acid (1S,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester Tadalafil Impurity 3 Tadalafil Impurity 11

Molecular Formula	C₂₀H₁₈N₂O₄
Molecular Weight	350.36800
Exact Mass	350.12700
PSA	72.58000
LogP	3.00210

120-57-0

64-17-5

73-22-3

171596-44-4

Detail

Literature: LEK Pharmaceuticals d.d. Patent: EP2107059 A1, 2009 ; Location in patent: Page/Page column 9 ;

120-57-0

4299-70-1

~36%

171596-44-4

171596-43-3

Literature: Daugan, Alain; Grondin, Pascal; Ruault, Cecile; Le Monnier de Gouville, Anne-Charlotte; Coste, Herve; Linget, Jean Michel; Kirilovsky, Jorge; Hyafil, Francois; Labaudinieret, Richard Journal of Medicinal Chemistry, 2003 , vol. 46, # 21 p. 4533 - 4542

120-57-0

7524-52-9

~95%

171596-43-3

Literature: Xiao, Sen; Shi, Xiao-Xin; Xing, Jing; Yan, Jing-Jing; Liu, Shi-Ling; Lu, Wei-Dong Tetrahedron Asymmetry, 2009 , vol. 20, # 18 p. 2090 - 2096

Precursor 5
120-57-0 64-17-5 73-22-3 4299-70-1
7524-52-9
DownStream 2
629652-72-8 171596-42-2

56-41-7	108-65-6
56-35-9	64-17-5
67-56-1	108-88-3
141-78-6	1310-73-2
13463-67-7	1333-86-4