Name | 6,7-dichloro-5-nitro-1,4-dihydroquinoxaline-2,3-dione |
---|---|
Synonyms |
6,7-Dichloro-5-nitro-2,3-quinoxalinedione
Licostinel 5-Nitro-6,7-dichloro-2,3-quinoxalinedione 2,3-Quinoxalinedione,6,7-dichloro-1,4-dihydro-5-nitro 5-nitro-6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione ACEA-1021 6,7-dichloro-1,4-dihydro-8-nitro-2,3-quinoxalinedione 1,4-dihydro-6,7-dichloro-5-nitroquinoxalin-2,3-dione 6,7-Dichloro-1,4-dihydro-5-nitro-2,3-quinoxalinedione |
Description | Licostinel (ACEA-1021) is a glycine receptor antagonist (IC50: 59 nM). Licostinel has neuroprotective activity[1][2][3]. |
---|---|
Related Catalog | |
Target |
59 nM (glycine receptor)[1] |
References |
Density | 1.757g/cm3 |
---|---|
Molecular Formula | C8H3Cl2N3O4 |
Molecular Weight | 276.03 |
Exact Mass | 274.95000 |
PSA | 111.54000 |
LogP | 1.95460 |
Index of Refraction | 1.647 |
~93% 153504-81-5 |
Literature: Keana; Kher; Sui Xiong Cai; Dinsmore; Glenn; Guastella; Huang; Ilyin; Lu; Mouser; Woodward; Weber Journal of Medicinal Chemistry, 1995 , vol. 38, # 22 p. 4367 - 4379 |
~88% 153504-81-5 |
Literature: Kher, Sunil M.; Cai, Sui Xiong; Weber, Eckard; Keana, John F. W. Journal of Organic Chemistry, 1995 , vol. 60, # 18 p. 5838 - 5842 |
~% 153504-81-5 |
Literature: Kher, Sunil M.; Cai, Sui Xiong; Weber, Eckard; Keana, John F. W. Journal of Organic Chemistry, 1995 , vol. 60, # 18 p. 5838 - 5842 |
~% 153504-81-5 |
Literature: Keana; Kher; Sui Xiong Cai; Dinsmore; Glenn; Guastella; Huang; Ilyin; Lu; Mouser; Woodward; Weber Journal of Medicinal Chemistry, 1995 , vol. 38, # 22 p. 4367 - 4379 |
~% 153504-81-5 |
Literature: Thorell, Jan-Olov; Stone-Elander, Sharon; Duelfer, Tim; Cai, Sui Xiong; Jones, Lawrence; Pfefferkorn, Heidi; Ciszewska, Grazyna Journal of Labelled Compounds and Radiopharmaceuticals, 1998 , vol. 41, # 4 p. 345 - 353 |
~% 153504-81-5 |
Literature: Thorell, Jan-Olov; Stone-Elander, Sharon; Duelfer, Tim; Cai, Sui Xiong; Jones, Lawrence; Pfefferkorn, Heidi; Ciszewska, Grazyna Journal of Labelled Compounds and Radiopharmaceuticals, 1998 , vol. 41, # 4 p. 345 - 353 |
~% 153504-81-5 |
Literature: Thorell, Jan-Olov; Stone-Elander, Sharon; Duelfer, Tim; Cai, Sui Xiong; Jones, Lawrence; Pfefferkorn, Heidi; Ciszewska, Grazyna Journal of Labelled Compounds and Radiopharmaceuticals, 1998 , vol. 41, # 4 p. 345 - 353 |
Precursor 7 | |
---|---|
DownStream 1 | |