- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Madecassic acid
- Price: Check
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Madecassic acid
- Price: ￥378.0/20mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: madecassic acid
- Price: $280.0/20mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Madecassic acid
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
18449-41-7
18449-41-7 structure
- Name: Madecassic acid
- Chemical Name: madecassic acid
- CAS Number: 18449-41-7
- Molecular Formula: C30H48O6
- Molecular Weight: 504.698
- Catalog: Natural product Moss
- Create Date: 2018-03-29 08:00:00
- Modify Date: 2025-08-20 21:38:37
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Madecassic acid is isolated from Centella asiatica (Umbelliferae). Madecassic acid has anti-inflammatory properties caused by iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-κB activation in RAW 264.7 macrophage cells[1].
| Name | madecassic acid |
|---|---|
| Synonyms |
Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2α,3β,5ξ,6β,9ξ,18ξ)-
Brahmanic acid (2α,3β,5ξ,6β,9ξ,18ξ)-2,3,6,23-Tetrahydroxyurs-12-en-28-oic acid 6-Hydroxyasiatic acid 6BETA-HYDROXYASIATIC ACID madecaic acid (2α,3β,6β)-2,3,6,23-Tetrahydroxyurs-12-en-28-oic acid madesica acid MADESIC ACID Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2α,3β,6β)- Madecassicacid Brahmsaeure (1S,2R,4aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,12bR,14bS)-8,10,11-Trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-4a(2H)-picenecarboxylic acid Hydroxy asiaticoside Brahmic acid |
| Description | Madecassic acid is isolated from Centella asiatica (Umbelliferae). Madecassic acid has anti-inflammatory properties caused by iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-κB activation in RAW 264.7 macrophage cells[1]. |
|---|---|
| Related Catalog | |
| Target |
COX-2 TNF-α IL-1β IL-6 |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 641.7±55.0 °C at 760 mmHg |
| Melting Point | 270ºC (dec.) |
| Molecular Formula | C30H48O6 |
| Molecular Weight | 504.698 |
| Flash Point | 355.9±28.0 °C |
| Exact Mass | 504.345093 |
| PSA | 118.22000 |
| LogP | 4.99 |
| Vapour Pressure | 0.0±4.3 mmHg at 25°C |
| Index of Refraction | 1.591 |
| Storage condition | 2-8°C |
|
~%
18449-41-7 |
| Literature: Phytochemistry (Elsevier), , vol. 7, p. 1385 - 1393 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |