97548-97-5
97548-97-5 structure
- Name: Quinelorane hydrochloride
- Chemical Name: (5aR,9aR)-6-propyl-5a,7,8,9,9a,10-hexahydro-5H-pyrido[2,3-g]quinazolin-2-amine,dihydrochloride
- CAS Number: 97548-97-5
- Molecular Formula: C14H24Cl2N4
- Molecular Weight: 319.27300
- Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
- Create Date: 2018-06-12 17:50:13
- Modify Date: 2024-01-09 12:11:17
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Quinelorane dihydrochloride (LY163502) is a potent dopamine D3/D2 receptor agonist. Quinelorane has the potential for neurological and psychiatric disorders research[1][2].
| Name | (5aR,9aR)-6-propyl-5a,7,8,9,9a,10-hexahydro-5H-pyrido[2,3-g]quinazolin-2-amine,dihydrochloride |
|---|---|
| Synonyms |
Quinelorane HCl
Quinelorane dihydrochloride LY-163,502 Quinerlorane hydrochloride |
| Description | Quinelorane dihydrochloride (LY163502) is a potent dopamine D3/D2 receptor agonist. Quinelorane has the potential for neurological and psychiatric disorders research[1][2]. |
|---|---|
| Related Catalog | |
| Target |
D2 Receptor D3 Receptor |
| In Vivo | Quinelorane dihydrochloride (LY163502; 0.003, 0.01 mg/kg; s.c.) reduces GABA efflux, with significant effects with 0.01 but not 0.003 mg/kg in male Wistar rats (300 g)[1]. Quinelorane dihydrochloride (0.032, 0.32, 3.2, 5.6 mg/kg; IP) significantly and dose-dependently increases locomotor activity in the Sprague Dawley rats. There was no main effect of sex and sex interaction[1]. Quinelorane dihydrochloride significantly decreases activity in the male and female inbred FVB/NJ, BALB/cJ, BALB/cByJ, C57BL/6J, Swiss Webster, A/J, DBA/2J, 129S1/SvImJ, and 129S6/SvEvTac mice[1]. |
| References |
| Boiling Point | 438.5ºC at 760 mmHg |
|---|---|
| Molecular Formula | C14H24Cl2N4 |
| Molecular Weight | 319.27300 |
| Flash Point | 219ºC |
| Exact Mass | 318.13800 |
| PSA | 55.04000 |
| LogP | 3.77110 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |