959151-50-9

959151-50-9 structure

Name: PF 750
Chemical Name: N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide
CAS Number: 959151-50-9
Molecular Formula: C₂₂H₂₃N₃O
Molecular Weight: 345.438
Catalog: Signaling Pathways Metabolic Enzyme/Protease FAAH
Create Date: 2017-08-10 06:02:29
Modify Date: 2025-08-25 19:04:24
PF 750 is a selective and covalent fatty acid amide hydrolase (FAAH) inhibitor, with IC50s varied from 16.2-595 nM in different pre-incubation times. Covalently modifies the enzyme’s active site serine nucleophile[1].

Name	N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide
Synonyms	N-Phenyl-4-(3-quinolinylmethyl)-1-piperidinecarboxamide 1-Piperidinecarboxamide, N-phenyl-4-(3-quinolinylmethyl)- N-Phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide PF-750 Nisoxetine hydrochloride

Description	PF 750 is a selective and covalent fatty acid amide hydrolase (FAAH) inhibitor, with IC50s varied from 16.2-595 nM in different pre-incubation times. Covalently modifies the enzyme’s active site serine nucleophile[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> FAAH Research Areas >> Metabolic Disease Signaling Pathways >> Neuronal Signaling >> FAAH
Target	IC50: 16.2-595 nM (FAAH)[1].
References	[1]. Ahn K, et al. Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry. 2007 Nov 13;46(45):13019-30.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
RIDADR	NONH for all modes of transport