Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Nicotinohydrazide
Price: ￥438.0/100g ￥138.0/25g
Purity: 97.0%
Stocking Period: 2 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Nicotinic hydrazide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

553-53-7

553-53-7 structure

Name: Nicotinohydrazide
Chemical Name: Nicotinohydrazide
CAS Number: 553-53-7
Molecular Formula: C₆H₇N₃O
Molecular Weight: 137.139
Catalog: Chemical reagent Organic reagent 肼
Create Date: 2018-06-27 08:39:43
Modify Date: 2024-01-02 09:51:09
Nicotinohydrazide (Nicotinic acid hydrazide) is a small molecular compound[1].

Name	Nicotinohydrazide
Synonyms	Nicotinohydrazide pyridine-3-carbohydrazide EINECS 209-041-0 MFCD00006383 3-Pyridinecarboxylic acid, hydrazide

Description	Nicotinohydrazide (Nicotinic acid hydrazide) is a small molecular compound[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Kruszynski R. A structural and theoretical study of intermolecular interactions in nicotinohydrazide dihydrochloride. Acta Crystallogr C. 2011 Feb;67(Pt 2):o52-6.

Density	1.2±0.1 g/cm3
Melting Point	159-161 °C(lit.)
Molecular Formula	C₆H₇N₃O
Molecular Weight	137.139
Exact Mass	137.058914
PSA	68.01000
LogP	-0.83
Index of Refraction	1.584
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QT1750000

CHEMICAL NAME :: Nicotinic acid, hydrazide

CAS REGISTRY NUMBER :: 553-53-7

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H7-N3-O

MOLECULAR WEIGHT :: 137.16

WISWESSER LINE NOTATION :: T6NJ CVMZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04178

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 7,691,1955 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 124 gm/kg/71W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :: ONCOBS Oncology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.21- 1967- Volume(issue)/page/year: 38,106,1981

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R40
Safety Phrases	S22-S26-S36/37/39
RIDADR	UN2811
WGK Germany	3
RTECS	QT1750000
Packaging Group	III
Hazard Class	6.1
HS Code	2933399090

93-60-7

~98%

553-53-7

Literature: Khan, Khalid Mohammad; Rasheed, Maimona; Ullah, Zia; Hayat, Safdar; Kaukab, Farhana; Choudhary, M. Iqbal; Ur-Rahman, Atta; Perveen, Shahnaz Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 7 p. 1381 - 1387

614-18-6

~82%

553-53-7

Literature: Zou, Liang-Hua; Reball, Jens; Mottweiler, Jakob; Bolm, Carsten Chemical Communications (Cambridge, United Kingdom), 2012 , vol. 48, # 92 p. 11307 - 11309,3

59-67-6

~94%

553-53-7

Literature: Elshaarawy, Reda F.M.; Janiakb, Christoph Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2011 , vol. 66, # 12 p. 1202 - 1208

98-92-0

~85%

553-53-7

Literature: Hassan, Heba A.; Abdel-Aziz, Mohamed; Abuo-Rahma, Gamal El-Din A.A.; Farag, Hassan H. Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 4 p. 1681 - 1692

10400-19-8

553-53-7

Literature: Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 52, # 10 p. 1318 - 1324

110925-43-4

553-53-7

23541-50-6

Literature: Pharmaceutical Chemistry Journal, , vol. 21, # 6 p. 398 - 402 Khimiko-Farmatsevticheskii Zhurnal, , vol. 21, # 6 p. 663 - 667

Precursor 6
93-60-7 614-18-6 59-67-6 98-92-0
10400-19-8 110925-43-4
DownStream 10
1094260-38-4 35607-27-3 500-22-1 141079-04-1
141079-09-6 3690-46-8 51362-49-3 21398-08-3
18960-15-1 59-67-6

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

553-53-7	23597-85-5
386715-32-8	5433-39-6
4226-39-5	15017-27-3
402479-94-1	3460-67-1
114659-73-3	519152-72-8