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643-12-9

643-12-9 structure
643-12-9 structure
  • Name: D-(+)-CHIRO-INOSITOL
  • Chemical Name: d-(+)-chiro-inositol
  • CAS Number: 643-12-9
  • Molecular Formula: C6H12O6
  • Molecular Weight: 180.156
  • Catalog: Biochemical Carbohydrate Monosaccharide
  • Create Date: 2018-05-17 08:00:00
  • Modify Date: 2024-01-06 10:05:48
  • D-chiro-Inositol is an epimer of myo-inositol found in certain mammalian glycosylphosphatidylinositol protein anchors and inositol phosphoglycans possessing insulin-like bioactivity. D-chiro-Inositol is used clinically for the treatment of polycystic ovary syndrome (PCOS) and diabetes mellitus, which can reduce hyperglycemia and ameliorate insulin resistance[1][2][3].

Name d-(+)-chiro-inositol
Synonyms cyclohexanehexol
D-Inositol
(1R,2R,3S,4S,5S,6S)-1,2,3,4,5,6-Cyclohexanehexol
1,2,3,4,5,6-Cyclohexanehexol, (1α,2α,3β,4α,5β,6β)-
(1R,2R,3S,4S,5S,6S)-Cyclohexane-1,2,3,4,5,6-hexol
(1R,2R,3S,4S,5S,6S)-Cyclohexan-1,2,3,4,5,6-hexol
1,2,4/3,5,6-hexahydroxycyclohexane
1D-chiro-Inositol
(+)-1,2,4/3,5,6-Inositol
cis-inositol
EINECS 211-394-0
D-Chiro-inositol(DCI)
D-CHIRO-INOSITOL(DISD)
MFCD00272608
D-(+)-Inositol
D-chiro-inositol
Description D-chiro-Inositol is an epimer of myo-inositol found in certain mammalian glycosylphosphatidylinositol protein anchors and inositol phosphoglycans possessing insulin-like bioactivity. D-chiro-Inositol is used clinically for the treatment of polycystic ovary syndrome (PCOS) and diabetes mellitus, which can reduce hyperglycemia and ameliorate insulin resistance[1][2][3].
Related Catalog
References

[1]. Ostlund RE Jr, et al. A stereospecific myo-inositol/D-chiro-inositol transporter in HepG2 liver cells. Identification with D-chiro-[3-3H]inositol. J Biol Chem. 1996 Apr 26;271(17):10073-8.

[2]. Zhao SS, et al. D-chiro-inositol effectively attenuates cholestasis in bile duct ligated rats by improving bile acidsecretion and attenuating oxidative stress. Acta Pharmacol Sin. 2018 Feb;39(2):213-221.

[3]. Cheng F, et al. chiro-Inositol Ameliorates High Fat Diet-Induced Hepatic Steatosis and Insulin Resistance viaPKCε-PI3K/AKT Pathway. J Agric Food Chem. 2019 May 29;67(21):5957-5967.

Density 2.0±0.1 g/cm3
Boiling Point 291.3±40.0 °C at 760 mmHg
Melting Point 230 °C
Molecular Formula C6H12O6
Molecular Weight 180.156
Flash Point 143.4±21.9 °C
Exact Mass 180.063385
PSA 121.38000
LogP -2.11
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.784
Storage condition Freezer
Hazard Codes Xn
Risk Phrases R20/21/22
Safety Phrases S24/25
HS Code 29061390
HS Code 29061390