95549-92-1

95549-92-1 structure

Name: Metazosin
Chemical Name: 1-Propanone, 1-[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-methoxy
CAS Number: 95549-92-1
Molecular Formula: C₁₈H₂₅N₅O₄
Molecular Weight: 375.42200
Create Date: 2017-02-07 15:13:51
Modify Date: 2025-08-27 10:49:13
Metazosin (Kenosin) is a potent α1 adrenoceptor blocker. Metazosin is an antihypertensive agent lowering blood pressure[1].

Name	1-Propanone, 1-[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-methoxy
Synonyms	1-(4-(4-AMINO-6,7-DIMETHOXYQUINAZOLIN-2-YL)PIPERAZIN-1-YL)-2-METHOXYPROPAN-1-ONE Metazosin Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-methoxy-1-oxopropyl)-

Description	Metazosin (Kenosin) is a potent α1 adrenoceptor blocker. Metazosin is an antihypertensive agent lowering blood pressure[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
In Vitro	Metazosin interacts with a-adrenoceptors both at the central and peripheral level[1].
References	[1]. Lapka R, et al. Interspecies pharmacokinetic scaling of metazosin, a novel alpha-adrenergic antagonist. Biopharm Drug Dispos. 1989;10(6):581-589.