Metazosin

Modify Date: 2024-01-08 18:02:24

Metazosin Structure
Metazosin structure
Common Name Metazosin
CAS Number 95549-92-1 Molecular Weight 375.42200
Density 1.274±0.06 g/cm3 (20 °C, 760 mmHg) Boiling Point 613.1±65.0 °C (760 mmHg)
Molecular Formula C18H25N5O4 Melting Point 214-221 °C
MSDS N/A Flash Point N/A

 Use of Metazosin


Metazosin (Kenosin) is a potent α1 adrenoceptor blocker. Metazosin is an antihypertensive agent lowering blood pressure[1].

 Names

Name 1-Propanone, 1-[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-methoxy
Synonym More Synonyms

 Metazosin Biological Activity

Description Metazosin (Kenosin) is a potent α1 adrenoceptor blocker. Metazosin is an antihypertensive agent lowering blood pressure[1].
Related Catalog
In Vitro Metazosin interacts with a-adrenoceptors both at the central and peripheral level[1].
References

[1]. Lapka R, et al. Interspecies pharmacokinetic scaling of metazosin, a novel alpha-adrenergic antagonist. Biopharm Drug Dispos. 1989;10(6):581-589.

 Chemical & Physical Properties

Density 1.274±0.06 g/cm3 (20 °C, 760 mmHg)
Boiling Point 613.1±65.0 °C (760 mmHg)
Melting Point 214-221 °C
Molecular Formula C18H25N5O4
Molecular Weight 375.42200
Exact Mass 375.19100
PSA 103.04000
LogP 1.49680

 Synonyms

1-(4-(4-AMINO-6,7-DIMETHOXYQUINAZOLIN-2-YL)PIPERAZIN-1-YL)-2-METHOXYPROPAN-1-ONE
Metazosin
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-methoxy-1-oxopropyl)-
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