29569-30-0

29569-30-0 structure

Name: 5-(2-Amino-2-oxoethyl)uridine
Chemical Name: 5-carbamoylmethyluridine
CAS Number: 29569-30-0
Molecular Formula: C₁₁H₁₅N₃O₇
Molecular Weight: 301.25
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-12-27 03:48:31
Modify Date: 2024-01-13 12:03:22
5-(2-Amino-2-oxoethyl)uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5-carbamoylmethyluridine
Synonyms	5-Cbmu 5-Carbamoylmethyluridine 5-uridinacetamide 5-(2-amino-2-oxoethyl)uridine 2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]acetamide

Description	5-(2-Amino-2-oxoethyl)uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.