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64199-78-6

64199-78-6 structure
64199-78-6 structure
  • Name: Barbinervic acid
  • Chemical Name: (1R,2R,4aS,6aS,6bR,8aR,9S,10R,12aR,12bR,14bS)-1,10-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid
  • CAS Number: 64199-78-6
  • Molecular Formula: C30H48O5
  • Molecular Weight: 488.70
  • Catalog: Natural product Moss
  • Create Date: 2016-12-16 19:59:26
  • Modify Date: 2024-04-03 21:37:01
  • Barbinervic acid is a glutaminase inhibitor with an IC50 of 14 μM. Barbinervic acid can be used for the study of neurodegenerative diseases[1].

Name (1R,2R,4aS,6aS,6bR,8aR,9S,10R,12aR,12bR,14bS)-1,10-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid
Synonyms (3α)-3,19,24-Trihydroxyurs-12-en-28-oic acid
Urs-12-en-28-oic acid, 3,19,24-trihydroxy-, (3α)-
Barbinervic acid
Description Barbinervic acid is a glutaminase inhibitor with an IC50 of 14 μM. Barbinervic acid can be used for the study of neurodegenerative diseases[1].
Related Catalog
References

[1]. Atsumi Shimada, et al. Pentacyclic triterpene acids, rotungenic acid and barbinervic acid, from fresh leaves of Diospyros kaki Thunberg and their glutaminase inhibitory activities. Nat Prod Res. 2022 Nov 26;1-5.  

Density 1.2±0.1 g/cm3
Boiling Point 622.8±55.0 °C at 760 mmHg
Melting Point 278-280 ºC
Molecular Formula C30H48O5
Molecular Weight 488.70
Flash Point 344.5±28.0 °C
Exact Mass 488.350189
PSA 97.99000
LogP 5.75
Vapour Pressure 0.0±4.1 mmHg at 25°C
Index of Refraction 1.581
Water Solubility Insuluble (1.8E-3 g/L) (25 ºC)
Hazard Codes Xi
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